Evolution of DNMT2 in drosophilids: Evidence for positive and purifying selection and insights into new protein (pathways) interactions

Evolution of DNMT2 in drosophilids: Evidence for positive and purifying selection and insights into new protein (pathways) interactions

Abstract The DNA methyltransferase 2 (DNMT2) protein is the most conserved member of the DNA methyltransferase family. Nevertheless, its substrate specificity is still controversial and elusive. The genomic role and determinants of DNA methylation are poorly understood in invertebrates, and several...

Full description

Bibliographic Details
Main Authors: Gilberto Cavalheiro Vieira, Marícia Fantinel D’Ávila, Rebeca Zanini, Maríndia Deprá, Vera Lúcia da Silva Valente
Format: Article
Language:English
Published: Sociedade Brasileira de Genética 2018-03-01
Series:Genetics and Molecular Biology
Subjects:
Drosophila
Dnmt2
positive selection
epigenetic
positive-destabilizing selection
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572018005005103&lng=en&tlng=en

Similar Items

Similar Items