Certainty of S100 from Physiology to Pathology

S100 exists in wide variety of tissues and cell types, originally isolated from brain tissue and they are of low molecular weight proteins. S100 is evenly distributed in cytoplasm and also in nucleoplasm and is involved in both intercellular and extracellular functions. S100 protein is generally e...

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Main Authors: Puneeth Horatti Kuberappa, Bhavana Shivanand Bagalad, Anuradha Ananthaneni, Md Asif Kiresur, Guduru Vijay Srinivas
Format: Article
Language:English
Published: JCDR Research and Publications Private Limited 2016-06-01
Series:Journal of Clinical and Diagnostic Research
Subjects:
Online Access:https://jcdr.net/articles/PDF/8022/17949_CE(EK)_F(AK)_PF1(SWAK)_PFA(AK)_PF2(PAG).pdf
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author Puneeth Horatti Kuberappa
Bhavana Shivanand Bagalad
Anuradha Ananthaneni
Md Asif Kiresur
Guduru Vijay Srinivas
author_facet Puneeth Horatti Kuberappa
Bhavana Shivanand Bagalad
Anuradha Ananthaneni
Md Asif Kiresur
Guduru Vijay Srinivas
author_sort Puneeth Horatti Kuberappa
collection DOAJ
description S100 exists in wide variety of tissues and cell types, originally isolated from brain tissue and they are of low molecular weight proteins. S100 is evenly distributed in cytoplasm and also in nucleoplasm and is involved in both intercellular and extracellular functions. S100 protein is generally expressed in normal and also in pathological conditions. In current review, we discuss: a) update nomenclature of the various S100 proteins, b) expression of S100 in oral diseases (different soft tissue tumors, odontogenic cyst and tumor) for diagnostic value and also to know their histogenesis, c) role of S100 and RAGE receptor in oral squamous cell carcinoma.
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spelling doaj.art-67ba0402e56f4356a69116e3480945bf2022-12-22T03:39:46ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2016-06-01106ZE10ZE1510.7860/JCDR/2016/17949.8022Certainty of S100 from Physiology to PathologyPuneeth Horatti Kuberappa0Bhavana Shivanand Bagalad1Anuradha Ananthaneni2Md Asif Kiresur3Guduru Vijay Srinivas4Senior Lecturer, Department of Oral Pathology and Microbiology, St Joseph Dental College, Eluru, Andhra Pradesh, India.Senior Lecturer, Department of Oral Pathology and Microbiology, St Joseph Dental College, Eluru, Andhra Pradesh, India.Professor, Department of Oral Pathology and Microbiology, St Joseph Dental College, Eluru, Andhra Pradesh, India.Senior Lecturer, Department of Oral Pathology and Microbiology, St Joseph Dental College, Eluru, Andhra Pradesh, India.Professor and Head, Department of Oral Pathology and Microbiology, St Joseph Dental College, Eluru, Andhra Pradesh, India.S100 exists in wide variety of tissues and cell types, originally isolated from brain tissue and they are of low molecular weight proteins. S100 is evenly distributed in cytoplasm and also in nucleoplasm and is involved in both intercellular and extracellular functions. S100 protein is generally expressed in normal and also in pathological conditions. In current review, we discuss: a) update nomenclature of the various S100 proteins, b) expression of S100 in oral diseases (different soft tissue tumors, odontogenic cyst and tumor) for diagnostic value and also to know their histogenesis, c) role of S100 and RAGE receptor in oral squamous cell carcinoma.https://jcdr.net/articles/PDF/8022/17949_CE(EK)_F(AK)_PF1(SWAK)_PFA(AK)_PF2(PAG).pdfodontogenic cyst and tumororal squamous cell carcinomasoft tissue tumors
spellingShingle Puneeth Horatti Kuberappa
Bhavana Shivanand Bagalad
Anuradha Ananthaneni
Md Asif Kiresur
Guduru Vijay Srinivas
Certainty of S100 from Physiology to Pathology
Journal of Clinical and Diagnostic Research
odontogenic cyst and tumor
oral squamous cell carcinoma
soft tissue tumors
title Certainty of S100 from Physiology to Pathology
title_full Certainty of S100 from Physiology to Pathology
title_fullStr Certainty of S100 from Physiology to Pathology
title_full_unstemmed Certainty of S100 from Physiology to Pathology
title_short Certainty of S100 from Physiology to Pathology
title_sort certainty of s100 from physiology to pathology
topic odontogenic cyst and tumor
oral squamous cell carcinoma
soft tissue tumors
url https://jcdr.net/articles/PDF/8022/17949_CE(EK)_F(AK)_PF1(SWAK)_PFA(AK)_PF2(PAG).pdf
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