Association of single nucleotide polymorphisms of miRNAs involved in the GLUT4 pathway in T2DM in a Chinese population

Association of single nucleotide polymorphisms of miRNAs involved in the GLUT4 pathway in T2DM in a Chinese population

Abstract Background The insulin/insulin receptor substrate (IRS)/phosphatidylinositol 3‐kinase (PI3K)/protein kinase B (Akt)/GLUT4 pathway plays a crucial role in insulin resistance and is closely associated with T2DM. Accumulating evidence indicates that miRNAs (such as miR‐135a, let‐7d, miR‐107, m...

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Bibliographic Details
Main Authors: Yiping Li, Chuanyin Li, Man Yang, Li Shi, Wenyu Tao, Keyu Shen, Xianli Li, Xiaoling Wang, Ying Yang, Yufeng Yao
Format: Article
Language:English
Published: Wiley 2019-09-01
Series:Molecular Genetics & Genomic Medicine
Subjects:
Chinese population
GLUT4 pathway
insulin resistance
microRNA
polymorphisms
T2DM
Online Access:https://doi.org/10.1002/mgg3.907

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