Characterization and evolutionary implications of the triad Asp-Xxx-Glu in group II phosphopantetheinyl transferases.

Characterization and evolutionary implications of the triad Asp-Xxx-Glu in group II phosphopantetheinyl transferases.

Phosphopantetheinyl transferases (PPTases), which play an essential role in both primary and secondary metabolism, are magnesium binding enzymes. In this study, we characterized the magnesium binding residues of all known group II PPTases by biochemical and evolutionary analysis. Our results suggest...

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Bibliographic Details
Main Authors: Yue-Yue Wang, Yu-Dong Li, Jian-Bo Liu, Xin-Xin Ran, Yuan-Yang Guo, Ni-Ni Ren, Xin Chen, Hui Jiang, Yong-Quan Li
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4103896?pdf=render

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