A simulation study on enhancing sterilization efficiency in medical plastics through gamma radiation optimization
Abstract Gamma radiation is progressively emerging as an effective method to enhance the sterilization efficiency of medical plastics including Polyvinyl chloride (PVC). The parameters of the radiation facility will affect the efficiency of radiation sterilization. To investigate these effects, we s...
| Main Authors: | , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2023-11-01
|
| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-023-47771-9 |
| _version_ | 1797452720870785024 |
|---|---|
| author | Xin Yuan Fang Liu Hongchi Zhou Bin Liu Guanda Li Peiguang Yan Guoping Li Xiaoru Luo Xuefeng Lyu Jinxing Cheng Fenglei Niu |
| author_facet | Xin Yuan Fang Liu Hongchi Zhou Bin Liu Guanda Li Peiguang Yan Guoping Li Xiaoru Luo Xuefeng Lyu Jinxing Cheng Fenglei Niu |
| author_sort | Xin Yuan |
| collection | DOAJ |
| description | Abstract Gamma radiation is progressively emerging as an effective method to enhance the sterilization efficiency of medical plastics including Polyvinyl chloride (PVC). The parameters of the radiation facility will affect the efficiency of radiation sterilization. To investigate these effects, we simulate the gamma radiation sterilization performance of PVC material sample using Monte Carlo Method. The simulation results indicated that compared with the sterilization time of 20–90 min from high-temperature steam sterilization of medical waste, by optimizing the parameters of the model radiation facility, the radiation sterilization time can be reduced to 6.61 min. The optimized model facility parameters are as follows: the gamma photon energy is 1.25 MeV, the model space is 300 × 300 × 300 cm3, the reflective layer material is concrete and its thickness is 8 cm, the PVC sample layer area is 100 × 100 cm2, the distance between the radiation source and the PVC sample layer is 150 cm, the energy deposition in the bottom layer of the PVC sample layer is 1.31315 × 10–6 MeV/g. This study offers a potentially feasible way for PVC sterilization, while also providing a crucial reference for the further promotion and application of radiation sterilization technology. |
| first_indexed | 2024-03-09T15:11:44Z |
| format | Article |
| id | doaj.art-67c04df08103464ea6a1528dd84d7990 |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-03-09T15:11:44Z |
| publishDate | 2023-11-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj.art-67c04df08103464ea6a1528dd84d79902023-11-26T13:18:28ZengNature PortfolioScientific Reports2045-23222023-11-0113111110.1038/s41598-023-47771-9A simulation study on enhancing sterilization efficiency in medical plastics through gamma radiation optimizationXin Yuan0Fang Liu1Hongchi Zhou2Bin Liu3Guanda Li4Peiguang Yan5Guoping Li6Xiaoru Luo7Xuefeng Lyu8Jinxing Cheng9Fenglei Niu10Beijing Key Laboratory of Passive Safety Technology for Nuclear Energy, School of Nuclear Science and Engineering, North China Electric Power UniversityBeijing Key Laboratory of Passive Safety Technology for Nuclear Energy, School of Nuclear Science and Engineering, North China Electric Power UniversityBeijing Key Laboratory of Passive Safety Technology for Nuclear Energy, School of Nuclear Science and Engineering, North China Electric Power UniversityBeijing Key Laboratory of Passive Safety Technology for Nuclear Energy, School of Nuclear Science and Engineering, North China Electric Power UniversityBeijing Key Laboratory of Passive Safety Technology for Nuclear Energy, School of Nuclear Science and Engineering, North China Electric Power UniversityShenzhen Key Laboratory of Laser Engineering, College of Physics and Optoelectronic Engineering, Shenzhen UniversityThe Institute of NBC Defense, Chinese PLA ArmyThe Institute of NBC Defense, Chinese PLA ArmyBeijing Key Laboratory of Passive Safety Technology for Nuclear Energy, School of Nuclear Science and Engineering, North China Electric Power UniversityInstitute of Nuclear and New Energy Technology, Tsinghua UniversityBeijing Key Laboratory of Passive Safety Technology for Nuclear Energy, School of Nuclear Science and Engineering, North China Electric Power UniversityAbstract Gamma radiation is progressively emerging as an effective method to enhance the sterilization efficiency of medical plastics including Polyvinyl chloride (PVC). The parameters of the radiation facility will affect the efficiency of radiation sterilization. To investigate these effects, we simulate the gamma radiation sterilization performance of PVC material sample using Monte Carlo Method. The simulation results indicated that compared with the sterilization time of 20–90 min from high-temperature steam sterilization of medical waste, by optimizing the parameters of the model radiation facility, the radiation sterilization time can be reduced to 6.61 min. The optimized model facility parameters are as follows: the gamma photon energy is 1.25 MeV, the model space is 300 × 300 × 300 cm3, the reflective layer material is concrete and its thickness is 8 cm, the PVC sample layer area is 100 × 100 cm2, the distance between the radiation source and the PVC sample layer is 150 cm, the energy deposition in the bottom layer of the PVC sample layer is 1.31315 × 10–6 MeV/g. This study offers a potentially feasible way for PVC sterilization, while also providing a crucial reference for the further promotion and application of radiation sterilization technology.https://doi.org/10.1038/s41598-023-47771-9 |
| spellingShingle | Xin Yuan Fang Liu Hongchi Zhou Bin Liu Guanda Li Peiguang Yan Guoping Li Xiaoru Luo Xuefeng Lyu Jinxing Cheng Fenglei Niu A simulation study on enhancing sterilization efficiency in medical plastics through gamma radiation optimization Scientific Reports |
| title | A simulation study on enhancing sterilization efficiency in medical plastics through gamma radiation optimization |
| title_full | A simulation study on enhancing sterilization efficiency in medical plastics through gamma radiation optimization |
| title_fullStr | A simulation study on enhancing sterilization efficiency in medical plastics through gamma radiation optimization |
| title_full_unstemmed | A simulation study on enhancing sterilization efficiency in medical plastics through gamma radiation optimization |
| title_short | A simulation study on enhancing sterilization efficiency in medical plastics through gamma radiation optimization |
| title_sort | simulation study on enhancing sterilization efficiency in medical plastics through gamma radiation optimization |
| url | https://doi.org/10.1038/s41598-023-47771-9 |
| work_keys_str_mv | AT xinyuan asimulationstudyonenhancingsterilizationefficiencyinmedicalplasticsthroughgammaradiationoptimization AT fangliu asimulationstudyonenhancingsterilizationefficiencyinmedicalplasticsthroughgammaradiationoptimization AT hongchizhou asimulationstudyonenhancingsterilizationefficiencyinmedicalplasticsthroughgammaradiationoptimization AT binliu asimulationstudyonenhancingsterilizationefficiencyinmedicalplasticsthroughgammaradiationoptimization AT guandali asimulationstudyonenhancingsterilizationefficiencyinmedicalplasticsthroughgammaradiationoptimization AT peiguangyan asimulationstudyonenhancingsterilizationefficiencyinmedicalplasticsthroughgammaradiationoptimization AT guopingli asimulationstudyonenhancingsterilizationefficiencyinmedicalplasticsthroughgammaradiationoptimization AT xiaoruluo asimulationstudyonenhancingsterilizationefficiencyinmedicalplasticsthroughgammaradiationoptimization AT xuefenglyu asimulationstudyonenhancingsterilizationefficiencyinmedicalplasticsthroughgammaradiationoptimization AT jinxingcheng asimulationstudyonenhancingsterilizationefficiencyinmedicalplasticsthroughgammaradiationoptimization AT fengleiniu asimulationstudyonenhancingsterilizationefficiencyinmedicalplasticsthroughgammaradiationoptimization AT xinyuan simulationstudyonenhancingsterilizationefficiencyinmedicalplasticsthroughgammaradiationoptimization AT fangliu simulationstudyonenhancingsterilizationefficiencyinmedicalplasticsthroughgammaradiationoptimization AT hongchizhou simulationstudyonenhancingsterilizationefficiencyinmedicalplasticsthroughgammaradiationoptimization AT binliu simulationstudyonenhancingsterilizationefficiencyinmedicalplasticsthroughgammaradiationoptimization AT guandali simulationstudyonenhancingsterilizationefficiencyinmedicalplasticsthroughgammaradiationoptimization AT peiguangyan simulationstudyonenhancingsterilizationefficiencyinmedicalplasticsthroughgammaradiationoptimization AT guopingli simulationstudyonenhancingsterilizationefficiencyinmedicalplasticsthroughgammaradiationoptimization AT xiaoruluo simulationstudyonenhancingsterilizationefficiencyinmedicalplasticsthroughgammaradiationoptimization AT xuefenglyu simulationstudyonenhancingsterilizationefficiencyinmedicalplasticsthroughgammaradiationoptimization AT jinxingcheng simulationstudyonenhancingsterilizationefficiencyinmedicalplasticsthroughgammaradiationoptimization AT fengleiniu simulationstudyonenhancingsterilizationefficiencyinmedicalplasticsthroughgammaradiationoptimization |