Effect of Cognitive Behavioral Therapy Versus Interpersonal Psychotherapy in Patients with Major Depressive Disorder: A Meta-analysis of Randomized Controlled Trials
Background: Practice guidelines have recommended cognitive behavioral therapy (CBT) and interpersonal psychotherapy (IPT) as the treatment of choice for major depression disorder (MDD). However, whether one therapy is better than the other remains inconclusive. The aim of this study was to compare t...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer
2017-01-01
|
| Series: | Chinese Medical Journal |
| Subjects: | |
| Online Access: | http://www.cmj.org/article.asp?issn=0366-6999;year=2017;volume=130;issue=23;spage=2844;epage=2851;aulast=Zhou |
| _version_ | 1818486578943623168 |
|---|---|
| author | She-Gang Zhou Yan-Fei Hou Ding Liu Xiao-Yuan Zhang |
| author_facet | She-Gang Zhou Yan-Fei Hou Ding Liu Xiao-Yuan Zhang |
| author_sort | She-Gang Zhou |
| collection | DOAJ |
| description | Background: Practice guidelines have recommended cognitive behavioral therapy (CBT) and interpersonal psychotherapy (IPT) as the treatment of choice for major depression disorder (MDD). However, whether one therapy is better than the other remains inconclusive. The aim of this study was to compare the treatment efficacy of the two treatment approaches for MDD.
Methods: Using the terms “cognitive behavior therapy or cognitive therapy or CBT or CT or cognitive behavioral therapy” and “interpersonal psychotherapy or IPT,” we systematically searched PubMed, Psyclnfo and Chinese National Knowledge Infrastructure databases up to February 2017. The language was restricted to be English and Chinese. Therapeutic outcomes, characteristics, and research quality were then extracted and analyzed independently. In accessing the included studies, we followed the criteria suggested by the Cochrane Handbook for Systematic Reviews of Interventions.
Results: Data for 946 patients from 10 randomized controlled trials were included in the study. Methodological quality was not optimal in most trials. Meta-analysis showed a mean difference (MD) of −1.31, 95% confidence interval (CI) (−2.49, −0.12) (P < 0.05) in favor of CBT according to the Beck Depression Inventory (BDI), and however, we did not found any statistically significant difference between CBT and IPT on the Hamilton Rating Scale for depression (HRSD) (MD −0.90, 95% CI [−2.18, 0.38]). Subgroup analyses for the studies in which patients were treated only by psychotherapy (MD −1.26, 95% CI [−2.78, 0.35]) and for those which offered more sessions of therapies (MD −0.82, 95% CI [−2.23, 0.59]) showed there was no significant difference between CBT and IPT according to BDI.
Conclusions: Differences in treatment efficacy seem to vary according to different outcome measures. CBT shows an advantage over IPT for MDD according to BDI, and there is no significant difference between the two according to HRSD. These results should be interpreted with caution. |
| first_indexed | 2024-12-10T16:24:52Z |
| format | Article |
| id | doaj.art-67c26e12556040c8a6c2b2439375cbc9 |
| institution | Directory Open Access Journal |
| issn | 0366-6999 |
| language | English |
| last_indexed | 2024-12-10T16:24:52Z |
| publishDate | 2017-01-01 |
| publisher | Wolters Kluwer |
| record_format | Article |
| series | Chinese Medical Journal |
| spelling | doaj.art-67c26e12556040c8a6c2b2439375cbc92022-12-22T01:41:42ZengWolters KluwerChinese Medical Journal0366-69992017-01-01130232844285110.4103/0366-6999.219149Effect of Cognitive Behavioral Therapy Versus Interpersonal Psychotherapy in Patients with Major Depressive Disorder: A Meta-analysis of Randomized Controlled TrialsShe-Gang ZhouYan-Fei HouDing LiuXiao-Yuan ZhangBackground: Practice guidelines have recommended cognitive behavioral therapy (CBT) and interpersonal psychotherapy (IPT) as the treatment of choice for major depression disorder (MDD). However, whether one therapy is better than the other remains inconclusive. The aim of this study was to compare the treatment efficacy of the two treatment approaches for MDD. Methods: Using the terms “cognitive behavior therapy or cognitive therapy or CBT or CT or cognitive behavioral therapy” and “interpersonal psychotherapy or IPT,” we systematically searched PubMed, Psyclnfo and Chinese National Knowledge Infrastructure databases up to February 2017. The language was restricted to be English and Chinese. Therapeutic outcomes, characteristics, and research quality were then extracted and analyzed independently. In accessing the included studies, we followed the criteria suggested by the Cochrane Handbook for Systematic Reviews of Interventions. Results: Data for 946 patients from 10 randomized controlled trials were included in the study. Methodological quality was not optimal in most trials. Meta-analysis showed a mean difference (MD) of −1.31, 95% confidence interval (CI) (−2.49, −0.12) (P < 0.05) in favor of CBT according to the Beck Depression Inventory (BDI), and however, we did not found any statistically significant difference between CBT and IPT on the Hamilton Rating Scale for depression (HRSD) (MD −0.90, 95% CI [−2.18, 0.38]). Subgroup analyses for the studies in which patients were treated only by psychotherapy (MD −1.26, 95% CI [−2.78, 0.35]) and for those which offered more sessions of therapies (MD −0.82, 95% CI [−2.23, 0.59]) showed there was no significant difference between CBT and IPT according to BDI. Conclusions: Differences in treatment efficacy seem to vary according to different outcome measures. CBT shows an advantage over IPT for MDD according to BDI, and there is no significant difference between the two according to HRSD. These results should be interpreted with caution.http://www.cmj.org/article.asp?issn=0366-6999;year=2017;volume=130;issue=23;spage=2844;epage=2851;aulast=ZhouCognitive Therapy; Major Depression Disorder; Psychotherapy |
| spellingShingle | She-Gang Zhou Yan-Fei Hou Ding Liu Xiao-Yuan Zhang Effect of Cognitive Behavioral Therapy Versus Interpersonal Psychotherapy in Patients with Major Depressive Disorder: A Meta-analysis of Randomized Controlled Trials Chinese Medical Journal Cognitive Therapy; Major Depression Disorder; Psychotherapy |
| title | Effect of Cognitive Behavioral Therapy Versus Interpersonal Psychotherapy in Patients with Major Depressive Disorder: A Meta-analysis of Randomized Controlled Trials |
| title_full | Effect of Cognitive Behavioral Therapy Versus Interpersonal Psychotherapy in Patients with Major Depressive Disorder: A Meta-analysis of Randomized Controlled Trials |
| title_fullStr | Effect of Cognitive Behavioral Therapy Versus Interpersonal Psychotherapy in Patients with Major Depressive Disorder: A Meta-analysis of Randomized Controlled Trials |
| title_full_unstemmed | Effect of Cognitive Behavioral Therapy Versus Interpersonal Psychotherapy in Patients with Major Depressive Disorder: A Meta-analysis of Randomized Controlled Trials |
| title_short | Effect of Cognitive Behavioral Therapy Versus Interpersonal Psychotherapy in Patients with Major Depressive Disorder: A Meta-analysis of Randomized Controlled Trials |
| title_sort | effect of cognitive behavioral therapy versus interpersonal psychotherapy in patients with major depressive disorder a meta analysis of randomized controlled trials |
| topic | Cognitive Therapy; Major Depression Disorder; Psychotherapy |
| url | http://www.cmj.org/article.asp?issn=0366-6999;year=2017;volume=130;issue=23;spage=2844;epage=2851;aulast=Zhou |
| work_keys_str_mv | AT shegangzhou effectofcognitivebehavioraltherapyversusinterpersonalpsychotherapyinpatientswithmajordepressivedisorderametaanalysisofrandomizedcontrolledtrials AT yanfeihou effectofcognitivebehavioraltherapyversusinterpersonalpsychotherapyinpatientswithmajordepressivedisorderametaanalysisofrandomizedcontrolledtrials AT dingliu effectofcognitivebehavioraltherapyversusinterpersonalpsychotherapyinpatientswithmajordepressivedisorderametaanalysisofrandomizedcontrolledtrials AT xiaoyuanzhang effectofcognitivebehavioraltherapyversusinterpersonalpsychotherapyinpatientswithmajordepressivedisorderametaanalysisofrandomizedcontrolledtrials |