DNA methylation signatures of chronic alcohol dependence in purified CD3+ T-cells of patients undergoing alcohol treatment

DNA methylation signatures of chronic alcohol dependence in purified CD3+ T-cells of patients undergoing alcohol treatment

Abstract Several studies have shown an association of alcohol dependence with DNA methylation (DNAm), suggesting that environmentally-induced changes on epigenomic variation may play an important role in alcohol dependence. In the present study, we analysed genome-wide DNAm profiles of purified CD3+...

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Bibliographic Details
Main Authors: Christof Brückmann, Sumaiya A. Islam, Julia L. MacIsaac, Alexander M. Morin, Kathrin N. Karle, Adriana Di Santo, Richard Wüst, Immanuel Lang, Anil Batra, Michael S. Kobor, Vanessa Nieratschker
Format: Article
Language:English
Published: Nature Portfolio 2017-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-06847-z

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