Looking ahead: giant-cell arteritis in 10 years time
Although great improvements have been achieved in the fields of diagnosing and treating patients with giant-cell arteritis (GCA) in the last decades, several questions remain unanswered. The progressive increase in the number of older people, together with growing awareness of the disease and use of...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2022-05-01
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| Series: | Therapeutic Advances in Musculoskeletal Disease |
| Online Access: | https://doi.org/10.1177/1759720X221096366 |
| _version_ | 1831517101440892928 |
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| author | Milena Bond Alessandro Tomelleri Frank Buttgereit Eric L. Matteson Christian Dejaco |
| author_facet | Milena Bond Alessandro Tomelleri Frank Buttgereit Eric L. Matteson Christian Dejaco |
| author_sort | Milena Bond |
| collection | DOAJ |
| description | Although great improvements have been achieved in the fields of diagnosing and treating patients with giant-cell arteritis (GCA) in the last decades, several questions remain unanswered. The progressive increase in the number of older people, together with growing awareness of the disease and use of advanced diagnostic tools by healthcare professionals, foretells a possible increase in both prevalence and number of newly diagnosed patients with GCA in the coming years. A thorough clarification of pathogenetic mechanisms and a better definition of clinical subsets are the first steps toward a better understanding of the disease and, subsequently, toward a better use of existing and future therapeutic options. Examination of the role of different imaging techniques for GCA diagnosing and monitoring, optimization, and personalization of glucocorticoids and other immunosuppressive agents, further development and introduction of novel drugs, identification of prognostic factors for long-term outcomes and management of treatment discontinuation will be the central topics of the research agenda in years to come. |
| first_indexed | 2024-04-14T00:14:16Z |
| format | Article |
| id | doaj.art-67cb09a651d845b08604cf81145e344a |
| institution | Directory Open Access Journal |
| issn | 1759-7218 |
| language | English |
| last_indexed | 2024-04-14T00:14:16Z |
| publishDate | 2022-05-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Therapeutic Advances in Musculoskeletal Disease |
| spelling | doaj.art-67cb09a651d845b08604cf81145e344a2022-12-22T02:23:11ZengSAGE PublishingTherapeutic Advances in Musculoskeletal Disease1759-72182022-05-011410.1177/1759720X221096366Looking ahead: giant-cell arteritis in 10 years timeMilena BondAlessandro TomelleriFrank ButtgereitEric L. MattesonChristian DejacoAlthough great improvements have been achieved in the fields of diagnosing and treating patients with giant-cell arteritis (GCA) in the last decades, several questions remain unanswered. The progressive increase in the number of older people, together with growing awareness of the disease and use of advanced diagnostic tools by healthcare professionals, foretells a possible increase in both prevalence and number of newly diagnosed patients with GCA in the coming years. A thorough clarification of pathogenetic mechanisms and a better definition of clinical subsets are the first steps toward a better understanding of the disease and, subsequently, toward a better use of existing and future therapeutic options. Examination of the role of different imaging techniques for GCA diagnosing and monitoring, optimization, and personalization of glucocorticoids and other immunosuppressive agents, further development and introduction of novel drugs, identification of prognostic factors for long-term outcomes and management of treatment discontinuation will be the central topics of the research agenda in years to come.https://doi.org/10.1177/1759720X221096366 |
| spellingShingle | Milena Bond Alessandro Tomelleri Frank Buttgereit Eric L. Matteson Christian Dejaco Looking ahead: giant-cell arteritis in 10 years time Therapeutic Advances in Musculoskeletal Disease |
| title | Looking ahead: giant-cell arteritis in 10 years time |
| title_full | Looking ahead: giant-cell arteritis in 10 years time |
| title_fullStr | Looking ahead: giant-cell arteritis in 10 years time |
| title_full_unstemmed | Looking ahead: giant-cell arteritis in 10 years time |
| title_short | Looking ahead: giant-cell arteritis in 10 years time |
| title_sort | looking ahead giant cell arteritis in 10 years time |
| url | https://doi.org/10.1177/1759720X221096366 |
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