Polymeric ethosomal gel loaded with nimodipine: Optimisation, pharmacokinetic and histopathological analysis

Polymeric ethosomal gel loaded with nimodipine: Optimisation, pharmacokinetic and histopathological analysis

This study was performed with the main objective of formulating and evaluating the potential of ethosomesl gel (Etho gel) to deliver nimodipine (NiM) for cardiovascular disease, a potent water insoluble anti-hypertensive drug via skin to reach the deeper layers of skin. The Box-Behnken design (BBD)...

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Bibliographic Details
Main Authors: Jamal Moideen Muthu Mohamed, Barkat A Khan, Vijaya Rajendran, Mohamed El-Sherbiny, Gamal Othman, Abdulrahman Bashir Ahmed Hussamuldin, Rasha Hamed Al-Serwi
Format: Article
Language:English
Published: Elsevier 2022-11-01
Series:Saudi Pharmaceutical Journal
Subjects:
Soy lecithin
Ethosomes
Nimodipine
Box Behnken design
Ex vivo permeation
Online Access:http://www.sciencedirect.com/science/article/pii/S1319016422002262

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