Host miRNAs-microbiota interactions in gastric cancer
Abstract It is widely acknowledged that gastric cancer seriously affects the quality of life and survival of patients. The correlation between the microbiota and gastric cancer has attracted extensive attention in recent years, nonetheless the specific mechanism of its impact on gastric cancer remai...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2022-01-01
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| Series: | Journal of Translational Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12967-022-03264-3 |
| _version_ | 1819280837196120064 |
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| author | Yan Yang Yingying Huang Wu Lin Jin Liu Xiangliu Chen Chuanzhi Chen Xiongfei Yu Lisong Teng |
| author_facet | Yan Yang Yingying Huang Wu Lin Jin Liu Xiangliu Chen Chuanzhi Chen Xiongfei Yu Lisong Teng |
| author_sort | Yan Yang |
| collection | DOAJ |
| description | Abstract It is widely acknowledged that gastric cancer seriously affects the quality of life and survival of patients. The correlation between the microbiota and gastric cancer has attracted extensive attention in recent years, nonetheless the specific mechanism of its impact on gastric cancer remain largely unclear. Recent studies have shown that in addition to its role in the host’s inflammatory and immune response, the microbiota can also affect the occurrence and development of gastric cancer by affecting the expression of miRNAs. This paper brings together all currently available data on miRNAs, microbiota and gastric cancer, and preliminarily describes the relationship among them. |
| first_indexed | 2024-12-24T00:50:08Z |
| format | Article |
| id | doaj.art-67cfcac45c58416f92b6022aab8a23bb |
| institution | Directory Open Access Journal |
| issn | 1479-5876 |
| language | English |
| last_indexed | 2024-12-24T00:50:08Z |
| publishDate | 2022-01-01 |
| publisher | BMC |
| record_format | Article |
| series | Journal of Translational Medicine |
| spelling | doaj.art-67cfcac45c58416f92b6022aab8a23bb2022-12-21T17:23:36ZengBMCJournal of Translational Medicine1479-58762022-01-012011810.1186/s12967-022-03264-3Host miRNAs-microbiota interactions in gastric cancerYan Yang0Yingying Huang1Wu Lin2Jin Liu3Xiangliu Chen4Chuanzhi Chen5Xiongfei Yu6Lisong Teng7Department of Surgical Oncology, The First Affiliated Hospital, School of Medicine, Zhejiang UniversityDepartment of Surgical Oncology, The First Affiliated Hospital, School of Medicine, Zhejiang UniversityDepartment of Surgical Oncology, The First Affiliated Hospital, School of Medicine, Zhejiang UniversityDepartment of Surgical Oncology, The First Affiliated Hospital, School of Medicine, Zhejiang UniversityDepartment of Surgical Oncology, The First Affiliated Hospital, School of Medicine, Zhejiang UniversityDepartment of Surgical Oncology, The First Affiliated Hospital, School of Medicine, Zhejiang UniversityDepartment of Surgical Oncology, The First Affiliated Hospital, School of Medicine, Zhejiang UniversityDepartment of Surgical Oncology, The First Affiliated Hospital, School of Medicine, Zhejiang UniversityAbstract It is widely acknowledged that gastric cancer seriously affects the quality of life and survival of patients. The correlation between the microbiota and gastric cancer has attracted extensive attention in recent years, nonetheless the specific mechanism of its impact on gastric cancer remain largely unclear. Recent studies have shown that in addition to its role in the host’s inflammatory and immune response, the microbiota can also affect the occurrence and development of gastric cancer by affecting the expression of miRNAs. This paper brings together all currently available data on miRNAs, microbiota and gastric cancer, and preliminarily describes the relationship among them.https://doi.org/10.1186/s12967-022-03264-3Gastric cancermiRNAsMicrobiotaMetabolic interactionsMicroenvironment |
| spellingShingle | Yan Yang Yingying Huang Wu Lin Jin Liu Xiangliu Chen Chuanzhi Chen Xiongfei Yu Lisong Teng Host miRNAs-microbiota interactions in gastric cancer Journal of Translational Medicine Gastric cancer miRNAs Microbiota Metabolic interactions Microenvironment |
| title | Host miRNAs-microbiota interactions in gastric cancer |
| title_full | Host miRNAs-microbiota interactions in gastric cancer |
| title_fullStr | Host miRNAs-microbiota interactions in gastric cancer |
| title_full_unstemmed | Host miRNAs-microbiota interactions in gastric cancer |
| title_short | Host miRNAs-microbiota interactions in gastric cancer |
| title_sort | host mirnas microbiota interactions in gastric cancer |
| topic | Gastric cancer miRNAs Microbiota Metabolic interactions Microenvironment |
| url | https://doi.org/10.1186/s12967-022-03264-3 |
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