The Role of Chitosan Oligosaccharide in Metabolic Syndrome: A Review of Possible Mechanisms
Metabolic syndrome, a cluster of metabolic disorders including central obesity, insulin resistance, hyperglycemia, dyslipidemia, and hypertension, has become a major public health problem worldwide. It is of great significance to develop natural products to prevent and treat metabolic syndrome. Chit...
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| Format: | Article |
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MDPI AG
2021-09-01
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| Series: | Marine Drugs |
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| Online Access: | https://www.mdpi.com/1660-3397/19/9/501 |
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| author | Wenjing Tao Geng Wang Jintao Wei |
| author_facet | Wenjing Tao Geng Wang Jintao Wei |
| author_sort | Wenjing Tao |
| collection | DOAJ |
| description | Metabolic syndrome, a cluster of metabolic disorders including central obesity, insulin resistance, hyperglycemia, dyslipidemia, and hypertension, has become a major public health problem worldwide. It is of great significance to develop natural products to prevent and treat metabolic syndrome. Chitosan oligosaccharide (COS) is an oligomer of chitosan prepared by the deacetylation of chitin, which is the second most abundant polymer in nature. In recent years, COS has received widespread attention due to its various biological activities. The present review will summarize the evidence from both in vitro and in vivo studies of the beneficial effects of COS on obesity, dyslipidemia, diabetes mellitus, hyperglycemia, and hypertension, and focus attention on possible mechanisms of the prevention and treatment of metabolic syndrome by COS. |
| first_indexed | 2024-03-10T07:29:58Z |
| format | Article |
| id | doaj.art-67d244aded6e4124b52e74f11baf89a9 |
| institution | Directory Open Access Journal |
| issn | 1660-3397 |
| language | English |
| last_indexed | 2024-03-10T07:29:58Z |
| publishDate | 2021-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Marine Drugs |
| spelling | doaj.art-67d244aded6e4124b52e74f11baf89a92023-11-22T13:58:45ZengMDPI AGMarine Drugs1660-33972021-09-0119950110.3390/md19090501The Role of Chitosan Oligosaccharide in Metabolic Syndrome: A Review of Possible MechanismsWenjing Tao0Geng Wang1Jintao Wei2Hubei Key Laboratory of Animal Embryo and Molecular Breeding, Institute of Animal Husbandry and Veterinary, Hubei Academy of Agricultural Sciences, Wuhan 430064, ChinaKey Laboratory of Molecular Animal Nutrition, Ministry of Education, College of Animal Science, Zhejiang University, Hangzhou 310058, ChinaHubei Key Laboratory of Animal Embryo and Molecular Breeding, Institute of Animal Husbandry and Veterinary, Hubei Academy of Agricultural Sciences, Wuhan 430064, ChinaMetabolic syndrome, a cluster of metabolic disorders including central obesity, insulin resistance, hyperglycemia, dyslipidemia, and hypertension, has become a major public health problem worldwide. It is of great significance to develop natural products to prevent and treat metabolic syndrome. Chitosan oligosaccharide (COS) is an oligomer of chitosan prepared by the deacetylation of chitin, which is the second most abundant polymer in nature. In recent years, COS has received widespread attention due to its various biological activities. The present review will summarize the evidence from both in vitro and in vivo studies of the beneficial effects of COS on obesity, dyslipidemia, diabetes mellitus, hyperglycemia, and hypertension, and focus attention on possible mechanisms of the prevention and treatment of metabolic syndrome by COS.https://www.mdpi.com/1660-3397/19/9/501chitosan oligosaccharidemetabolic syndromeobesitydiabeteshypertension |
| spellingShingle | Wenjing Tao Geng Wang Jintao Wei The Role of Chitosan Oligosaccharide in Metabolic Syndrome: A Review of Possible Mechanisms Marine Drugs chitosan oligosaccharide metabolic syndrome obesity diabetes hypertension |
| title | The Role of Chitosan Oligosaccharide in Metabolic Syndrome: A Review of Possible Mechanisms |
| title_full | The Role of Chitosan Oligosaccharide in Metabolic Syndrome: A Review of Possible Mechanisms |
| title_fullStr | The Role of Chitosan Oligosaccharide in Metabolic Syndrome: A Review of Possible Mechanisms |
| title_full_unstemmed | The Role of Chitosan Oligosaccharide in Metabolic Syndrome: A Review of Possible Mechanisms |
| title_short | The Role of Chitosan Oligosaccharide in Metabolic Syndrome: A Review of Possible Mechanisms |
| title_sort | role of chitosan oligosaccharide in metabolic syndrome a review of possible mechanisms |
| topic | chitosan oligosaccharide metabolic syndrome obesity diabetes hypertension |
| url | https://www.mdpi.com/1660-3397/19/9/501 |
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