Solid pseudopapillary neoplasm of the pancreas: CT imaging features and radiologic-pathologic correlation
PURPOSE:We aimed to evaluate the imaging features of solid pseudopapillary neoplasm (SPN) of the pancreas with an emphasis on radiologic-pathologic correlation.METHODS:Ten patients (all female; mean age, 32 years) with histologic or cytologic diagnosis of SPN encountered between January 2007 and Dec...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Galenos Publishing House
2017-03-01
|
| Series: | Diagnostic and Interventional Radiology |
| Online Access: |
http://www.dirjournal.org/archives/archive-detail/article-preview/solid-pseudopapillary-neoplasm-of-the-pancreas-ct-/55323
|
| _version_ | 1827823371527651328 |
|---|---|
| author | Gopinathan Anil Junwei Zhang Nawal Ebrahim Al-Hamar Min En Nga |
| author_facet | Gopinathan Anil Junwei Zhang Nawal Ebrahim Al-Hamar Min En Nga |
| author_sort | Gopinathan Anil |
| collection | DOAJ |
| description | PURPOSE:We aimed to evaluate the imaging features of solid pseudopapillary neoplasm (SPN) of the pancreas with an emphasis on radiologic-pathologic correlation.METHODS:Ten patients (all female; mean age, 32 years) with histologic or cytologic diagnosis of SPN encountered between January 2007 and December 2013 were included in this study. Preoperative computed tomography (CT) images were reviewed for location, attenuation, enhancement pattern, margin, shape, size, morphology, presence of capsule and calcification. CT appearances were correlated with histopathologic findings. RESULTS:Tumors in the distal pancreatic body and tail had a tendency to be larger (mean size 12.6 cm vs. 4.0 cm). Six of the nine tumors that were resected had a fibrous pseudocapsule at histology, five of which could be identified on CT scan. Eight lesions had mixed hypoenhancing solid components and cystic areas corresponding to tumor necrosis and hemorrhage. The two smallest lesions were purely solid and nonencapsulated. Varied patterns of calcification were seen in four tumors. Three of the four pancreatic tail tumors invaded the spleen. At a median follow-up of 53 months, there was no evidence of recurrence in the nine patients who underwent surgical resection of the tumor.CONCLUSION:A mixed solid and cystic pancreatic mass in a young woman is suggestive of SPN. However, smaller lesions may be completely solid. Splenic invasion can occur in pancreatic tail SPNs; however, in this series it did not adversely affect the long-term outcome. |
| first_indexed | 2024-03-12T02:10:07Z |
| format | Article |
| id | doaj.art-67d3819fe16b4e208da4f41d5f8cbff4 |
| institution | Directory Open Access Journal |
| issn | 1305-3825 1305-3612 |
| language | English |
| last_indexed | 2024-03-12T02:10:07Z |
| publishDate | 2017-03-01 |
| publisher | Galenos Publishing House |
| record_format | Article |
| series | Diagnostic and Interventional Radiology |
| spelling | doaj.art-67d3819fe16b4e208da4f41d5f8cbff42023-09-06T13:28:41ZengGalenos Publishing HouseDiagnostic and Interventional Radiology1305-38251305-36122017-03-01232949910.5152/dir.2016.1610413049054Solid pseudopapillary neoplasm of the pancreas: CT imaging features and radiologic-pathologic correlationGopinathan Anil0Junwei Zhang1Nawal Ebrahim Al-Hamar2Min En Nga3 Department of Diagnostic Imaging, National University Hospital, Singapore; Department of Diagnostic Radiology, National University of Singapore Yong Loo Lin School of Medicine, Singapore Department of Diagnostic Imaging, National University Hospital, Singapore. Department of Diagnostic Imaging, National University Hospital, Singapore. Department of Pathology, National University Hospital, Singapore; Department of Pathology, National University of Singapore Yong Loo Lin School of Medicine, Singapore PURPOSE:We aimed to evaluate the imaging features of solid pseudopapillary neoplasm (SPN) of the pancreas with an emphasis on radiologic-pathologic correlation.METHODS:Ten patients (all female; mean age, 32 years) with histologic or cytologic diagnosis of SPN encountered between January 2007 and December 2013 were included in this study. Preoperative computed tomography (CT) images were reviewed for location, attenuation, enhancement pattern, margin, shape, size, morphology, presence of capsule and calcification. CT appearances were correlated with histopathologic findings. RESULTS:Tumors in the distal pancreatic body and tail had a tendency to be larger (mean size 12.6 cm vs. 4.0 cm). Six of the nine tumors that were resected had a fibrous pseudocapsule at histology, five of which could be identified on CT scan. Eight lesions had mixed hypoenhancing solid components and cystic areas corresponding to tumor necrosis and hemorrhage. The two smallest lesions were purely solid and nonencapsulated. Varied patterns of calcification were seen in four tumors. Three of the four pancreatic tail tumors invaded the spleen. At a median follow-up of 53 months, there was no evidence of recurrence in the nine patients who underwent surgical resection of the tumor.CONCLUSION:A mixed solid and cystic pancreatic mass in a young woman is suggestive of SPN. However, smaller lesions may be completely solid. Splenic invasion can occur in pancreatic tail SPNs; however, in this series it did not adversely affect the long-term outcome. http://www.dirjournal.org/archives/archive-detail/article-preview/solid-pseudopapillary-neoplasm-of-the-pancreas-ct-/55323 |
| spellingShingle | Gopinathan Anil Junwei Zhang Nawal Ebrahim Al-Hamar Min En Nga Solid pseudopapillary neoplasm of the pancreas: CT imaging features and radiologic-pathologic correlation Diagnostic and Interventional Radiology |
| title | Solid pseudopapillary neoplasm of the pancreas: CT imaging features and radiologic-pathologic correlation |
| title_full | Solid pseudopapillary neoplasm of the pancreas: CT imaging features and radiologic-pathologic correlation |
| title_fullStr | Solid pseudopapillary neoplasm of the pancreas: CT imaging features and radiologic-pathologic correlation |
| title_full_unstemmed | Solid pseudopapillary neoplasm of the pancreas: CT imaging features and radiologic-pathologic correlation |
| title_short | Solid pseudopapillary neoplasm of the pancreas: CT imaging features and radiologic-pathologic correlation |
| title_sort | solid pseudopapillary neoplasm of the pancreas ct imaging features and radiologic pathologic correlation |
| url |
http://www.dirjournal.org/archives/archive-detail/article-preview/solid-pseudopapillary-neoplasm-of-the-pancreas-ct-/55323
|
| work_keys_str_mv | AT gopinathananil solidpseudopapillaryneoplasmofthepancreasctimagingfeaturesandradiologicpathologiccorrelation AT junweizhang solidpseudopapillaryneoplasmofthepancreasctimagingfeaturesandradiologicpathologiccorrelation AT nawalebrahimalhamar solidpseudopapillaryneoplasmofthepancreasctimagingfeaturesandradiologicpathologiccorrelation AT minennga solidpseudopapillaryneoplasmofthepancreasctimagingfeaturesandradiologicpathologiccorrelation |