Assembly drives regioselective azide-alkyne cycloaddition reaction

Assembly drives regioselective azide-alkyne cycloaddition reaction

Abstract Azide-alkyne cycloaddition reaction is a very common organic reaction to synthesize nitrogen-containing heterocycles. Once catalyzed by Cu(I) or Ru(II), it turns out to be a click reaction and thus is widely applied in chemical biology for labeling. However, besides their poor regioselectiv...

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Bibliographic Details
Main Authors:	Qiaochu Jiang, Wenjun Zhan, Xiaoyang Liu, Lin Bai, Manli Wang, Ying Xu, Gaolin Liang
Format:	Article
Language:	English
Published:	Nature Portfolio 2023-07-01
Series:	Nature Communications
Online Access:	https://doi.org/10.1038/s41467-023-39658-0

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