Bilateral adrenal giant medullary lipoma combined with disorders of sex development: a rare case report and literature review
Bilateral adrenal myelolipoma is rare in clinics and patients with disorders of sex development (DSDs). One case was reported in our center. A 45-year-old patient was admitted to the hospital after discovering a left abdominal mass for more than a year and worsening abdominal pain for 18 days. An im...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-08-01
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| Series: | Frontiers in Oncology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fonc.2023.1210679/full |
| _version_ | 1797738184923152384 |
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| author | Chenghao Zhanghuang Chenghao Zhanghuang Na Long Zhen Yang Yucheng Xie Yucheng Xie |
| author_facet | Chenghao Zhanghuang Chenghao Zhanghuang Na Long Zhen Yang Yucheng Xie Yucheng Xie |
| author_sort | Chenghao Zhanghuang |
| collection | DOAJ |
| description | Bilateral adrenal myelolipoma is rare in clinics and patients with disorders of sex development (DSDs). One case was reported in our center. A 45-year-old patient was admitted to the hospital after discovering a left abdominal mass for more than a year and worsening abdominal pain for 18 days. An imaging examination showed bilateral adrenal masses. Physical examination showed clitoris hypertrophy with patelliform changes, thick and dense pubic hair, normal development of bilateral labia majora without labia minora, and urethral opening. After the relevant preoperative examinations, bilateral adrenal mass resection was performed under general anesthesia. The postoperative pathology confirmed adrenal myelolipoma. The incision healed well without recurrence over 10 years after the operation. Her enlarged clitoris decreased in size. This case report has a detailed diagnosis and treatment process and sufficient examination results. It can provide a reference for diagnosing and treating patients with bilateral adrenal myelolipoma and DSD and reduce the risk of misdiagnosis and mistreatment. |
| first_indexed | 2024-03-12T13:39:22Z |
| format | Article |
| id | doaj.art-67d653c8a34340058e0fd09c8c554937 |
| institution | Directory Open Access Journal |
| issn | 2234-943X |
| language | English |
| last_indexed | 2024-03-12T13:39:22Z |
| publishDate | 2023-08-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Oncology |
| spelling | doaj.art-67d653c8a34340058e0fd09c8c5549372023-08-23T23:30:05ZengFrontiers Media S.A.Frontiers in Oncology2234-943X2023-08-011310.3389/fonc.2023.12106791210679Bilateral adrenal giant medullary lipoma combined with disorders of sex development: a rare case report and literature reviewChenghao Zhanghuang0Chenghao Zhanghuang1Na Long2Zhen Yang3Yucheng Xie4Yucheng Xie5Department of Urology, Kunming Children’s Hospital, Yunnan Province Clinical Research Center for Children’s Health and Disease, Kunming, ChinaYunnan Key Laboratory of Children’s Major Disease Research, Yunnan Clinical Medical Center for Pediatric Diseases, Kunming Children’s Hospital, Kunming, ChinaSpecial Ward, Kunming Children’s Hospital, Yunnan Province Clinical Research Center for Children’s Health and Disease, Kunming, ChinaDepartment of Oncology, Yunnan Children Solid Tumor Treatment Center, Kunming Children’s Hospital, Kunming, ChinaDepartment of Pathology, Kunming Children’s Hospital, Kunming, ChinaDepartment of Pathology, The Second People’s Hospital of Yunnan Province, Kunming, ChinaBilateral adrenal myelolipoma is rare in clinics and patients with disorders of sex development (DSDs). One case was reported in our center. A 45-year-old patient was admitted to the hospital after discovering a left abdominal mass for more than a year and worsening abdominal pain for 18 days. An imaging examination showed bilateral adrenal masses. Physical examination showed clitoris hypertrophy with patelliform changes, thick and dense pubic hair, normal development of bilateral labia majora without labia minora, and urethral opening. After the relevant preoperative examinations, bilateral adrenal mass resection was performed under general anesthesia. The postoperative pathology confirmed adrenal myelolipoma. The incision healed well without recurrence over 10 years after the operation. Her enlarged clitoris decreased in size. This case report has a detailed diagnosis and treatment process and sufficient examination results. It can provide a reference for diagnosing and treating patients with bilateral adrenal myelolipoma and DSD and reduce the risk of misdiagnosis and mistreatment.https://www.frontiersin.org/articles/10.3389/fonc.2023.1210679/fulladrenal myelolipomaadrenal glanddisorders of sex development (DSD)diagnosispathology |
| spellingShingle | Chenghao Zhanghuang Chenghao Zhanghuang Na Long Zhen Yang Yucheng Xie Yucheng Xie Bilateral adrenal giant medullary lipoma combined with disorders of sex development: a rare case report and literature review Frontiers in Oncology adrenal myelolipoma adrenal gland disorders of sex development (DSD) diagnosis pathology |
| title | Bilateral adrenal giant medullary lipoma combined with disorders of sex development: a rare case report and literature review |
| title_full | Bilateral adrenal giant medullary lipoma combined with disorders of sex development: a rare case report and literature review |
| title_fullStr | Bilateral adrenal giant medullary lipoma combined with disorders of sex development: a rare case report and literature review |
| title_full_unstemmed | Bilateral adrenal giant medullary lipoma combined with disorders of sex development: a rare case report and literature review |
| title_short | Bilateral adrenal giant medullary lipoma combined with disorders of sex development: a rare case report and literature review |
| title_sort | bilateral adrenal giant medullary lipoma combined with disorders of sex development a rare case report and literature review |
| topic | adrenal myelolipoma adrenal gland disorders of sex development (DSD) diagnosis pathology |
| url | https://www.frontiersin.org/articles/10.3389/fonc.2023.1210679/full |
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