Endometriosis and Ovarian Cancer: Should we be worried? Five Cases Report and Literature Review
Endometriosis is a chronic inflammatory disease caused by the presence of extra-uterine endometrial tissue that affects women of reproductive age. Although the etiology remains not totally elucidated, recent advances in molecular technology, especially the ability for whole genome sequencing, have...
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Format: | Article |
Language: | English |
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José de Mello Saúde
2023-12-01
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Series: | Gazeta Médica |
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Online Access: | http://www.gazetamedica.com/index.php/gazeta/article/view/722 |
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author | José Silva Pereira Mónica Nave Marta Magro |
author_facet | José Silva Pereira Mónica Nave Marta Magro |
author_sort | José Silva Pereira |
collection | DOAJ |
description |
Endometriosis is a chronic inflammatory disease caused by the presence of extra-uterine endometrial tissue that affects women of reproductive age. Although the etiology remains not totally elucidated, recent advances in molecular technology, especially the ability for whole genome sequencing, have gradually revealed both genetic and epigenetic backgrounds for the development of the disease. Endometriosis has been recognized as a precursor lesion for certain types of ovarian cancer (endometriosis-associated ovarian cancers - EAOC) and the knowledge of this malignant potential is of paramount importance to seek for predictive factors and to select patients at risk. We report five different EAOC cases in our recent clinical practice, in order to draw attention to this issue through a literature review, and to provide clinicians with tools to communicate accurately and effectively with patients with endometriosis about their risk of ovarian cancer.
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first_indexed | 2024-03-08T21:21:17Z |
format | Article |
id | doaj.art-67d872e6722d43b2a726df92397a3010 |
institution | Directory Open Access Journal |
issn | 2183-8135 2184-0628 |
language | English |
last_indexed | 2024-03-08T21:21:17Z |
publishDate | 2023-12-01 |
publisher | José de Mello Saúde |
record_format | Article |
series | Gazeta Médica |
spelling | doaj.art-67d872e6722d43b2a726df92397a30102023-12-21T10:07:03ZengJosé de Mello SaúdeGazeta Médica2183-81352184-06282023-12-0111Endometriosis and Ovarian Cancer: Should we be worried? Five Cases Report and Literature ReviewJosé Silva Pereira0https://orcid.org/0000-0002-2636-2259Mónica Nave1https://orcid.org/0000-0001-5881-796XMarta Magro2https://orcid.org/0009-0007-0065-6279Gynecology Department at Hospital Prof. Dr. Fernando Fonseca, Amadora, Portugal; CUF Institute of Oncology, Hospital CUF Descobertas, Lisboa, Portugal.Oncology Department, Hospital da Luz, Lisboa, Portugal.Hospital CUF Sintra, Sintra, Portugal. Endometriosis is a chronic inflammatory disease caused by the presence of extra-uterine endometrial tissue that affects women of reproductive age. Although the etiology remains not totally elucidated, recent advances in molecular technology, especially the ability for whole genome sequencing, have gradually revealed both genetic and epigenetic backgrounds for the development of the disease. Endometriosis has been recognized as a precursor lesion for certain types of ovarian cancer (endometriosis-associated ovarian cancers - EAOC) and the knowledge of this malignant potential is of paramount importance to seek for predictive factors and to select patients at risk. We report five different EAOC cases in our recent clinical practice, in order to draw attention to this issue through a literature review, and to provide clinicians with tools to communicate accurately and effectively with patients with endometriosis about their risk of ovarian cancer. http://www.gazetamedica.com/index.php/gazeta/article/view/722EndometriosisOvarian Neoplasms |
spellingShingle | José Silva Pereira Mónica Nave Marta Magro Endometriosis and Ovarian Cancer: Should we be worried? Five Cases Report and Literature Review Gazeta Médica Endometriosis Ovarian Neoplasms |
title | Endometriosis and Ovarian Cancer: Should we be worried? Five Cases Report and Literature Review |
title_full | Endometriosis and Ovarian Cancer: Should we be worried? Five Cases Report and Literature Review |
title_fullStr | Endometriosis and Ovarian Cancer: Should we be worried? Five Cases Report and Literature Review |
title_full_unstemmed | Endometriosis and Ovarian Cancer: Should we be worried? Five Cases Report and Literature Review |
title_short | Endometriosis and Ovarian Cancer: Should we be worried? Five Cases Report and Literature Review |
title_sort | endometriosis and ovarian cancer should we be worried five cases report and literature review |
topic | Endometriosis Ovarian Neoplasms |
url | http://www.gazetamedica.com/index.php/gazeta/article/view/722 |
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