Neural innervation stimulates splenic TFF2 to arrest myeloid cell expansion and cancer
During colorectal inflammation and cancer, myeloid cells accumulate in the spleen and suppress the host immunity response. In this study, the authors use a mouse model of colitis to demonstrate that upon vagus stimulation splenic memory T cells release TFF2, which suppresses the expansion of myeloid...
| Main Authors: | , , , , , , , , , , , , , , , , , , |
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| 格式: | 文件 |
| 语言: | English |
| 出版: |
Nature Portfolio
2016-02-01
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| 丛编: | Nature Communications |
| 在线阅读: | https://doi.org/10.1038/ncomms10517 |