High Glucose-Induced Reactive Oxygen Species Stimulates Human Mesenchymal Stem Cell Migration Through Snail and EZH2-Dependent E-Cadherin Repression

High Glucose-Induced Reactive Oxygen Species Stimulates Human Mesenchymal Stem Cell Migration Through Snail and EZH2-Dependent E-Cadherin Repression

Background/Aims: Glucose plays an important role in stem cell fate determination and behaviors. However, it is still not known how glucose contributes to the precise molecular mechanisms responsible for stem cell migration. Thus, we investigate the effect of glucose on the regulation of the human um...

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Bibliographic Details
Main Authors: Ji Young Oh, Gee Euhn Choi, Hyun Jik Lee, Young Hyun Jung, So Hee Ko, Chang Woo Chae, Jun Sung Kim, Seo Yihl Kim, Jae Ryong Lim, Chang-Kyu Lee, Ho Jae Han
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2018-04-01
Series:Cellular Physiology and Biochemistry
Subjects:
High glucose
E-cadherin
Umbilical cord blood derived mesenchymal stem cells
Migration
Wound healing
Online Access:https://www.karger.com/Article/FullText/489360

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