Triple artemisinin-containing combination anti-malarial treatments should be implemented now to delay the emergence of resistance: the case against

Abstract Managing multidrug resistant malaria can be problematic if currently available artemisinin-containing anti-malarial combination treatments are not used appropriately. Here, I debate that the best way to manage multidrug resistant malaria is to make best use of existing treatments and to dev...

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Main Author: Sanjeev Krishna
Format: Article
Language:English
Published: BMC 2019-10-01
Series:Malaria Journal
Online Access:http://link.springer.com/article/10.1186/s12936-019-2976-7
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author Sanjeev Krishna
author_facet Sanjeev Krishna
author_sort Sanjeev Krishna
collection DOAJ
description Abstract Managing multidrug resistant malaria can be problematic if currently available artemisinin-containing anti-malarial combination treatments are not used appropriately. Here, I debate that the best way to manage multidrug resistant malaria is to make best use of existing treatments and to develop new classes of anti-malarial drugs and not to make ‘triple combination therapies’ when there is already resistance to one or more proposed components.
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spelling doaj.art-67e4387191e5428894934e483a7c8fc72022-12-22T02:53:58ZengBMCMalaria Journal1475-28752019-10-011811310.1186/s12936-019-2976-7Triple artemisinin-containing combination anti-malarial treatments should be implemented now to delay the emergence of resistance: the case againstSanjeev Krishna0Centre for Diagnostics and Antimicrobial Resistance, Institute for Infection & Immunity, St. George’s, University of LondonAbstract Managing multidrug resistant malaria can be problematic if currently available artemisinin-containing anti-malarial combination treatments are not used appropriately. Here, I debate that the best way to manage multidrug resistant malaria is to make best use of existing treatments and to develop new classes of anti-malarial drugs and not to make ‘triple combination therapies’ when there is already resistance to one or more proposed components.http://link.springer.com/article/10.1186/s12936-019-2976-7
spellingShingle Sanjeev Krishna
Triple artemisinin-containing combination anti-malarial treatments should be implemented now to delay the emergence of resistance: the case against
Malaria Journal
title Triple artemisinin-containing combination anti-malarial treatments should be implemented now to delay the emergence of resistance: the case against
title_full Triple artemisinin-containing combination anti-malarial treatments should be implemented now to delay the emergence of resistance: the case against
title_fullStr Triple artemisinin-containing combination anti-malarial treatments should be implemented now to delay the emergence of resistance: the case against
title_full_unstemmed Triple artemisinin-containing combination anti-malarial treatments should be implemented now to delay the emergence of resistance: the case against
title_short Triple artemisinin-containing combination anti-malarial treatments should be implemented now to delay the emergence of resistance: the case against
title_sort triple artemisinin containing combination anti malarial treatments should be implemented now to delay the emergence of resistance the case against
url http://link.springer.com/article/10.1186/s12936-019-2976-7
work_keys_str_mv AT sanjeevkrishna tripleartemisinincontainingcombinationantimalarialtreatmentsshouldbeimplementednowtodelaytheemergenceofresistancethecaseagainst