Triple artemisinin-containing combination anti-malarial treatments should be implemented now to delay the emergence of resistance: the case against
Abstract Managing multidrug resistant malaria can be problematic if currently available artemisinin-containing anti-malarial combination treatments are not used appropriately. Here, I debate that the best way to manage multidrug resistant malaria is to make best use of existing treatments and to dev...
Main Author: | |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2019-10-01
|
Series: | Malaria Journal |
Online Access: | http://link.springer.com/article/10.1186/s12936-019-2976-7 |
_version_ | 1811306134834774016 |
---|---|
author | Sanjeev Krishna |
author_facet | Sanjeev Krishna |
author_sort | Sanjeev Krishna |
collection | DOAJ |
description | Abstract Managing multidrug resistant malaria can be problematic if currently available artemisinin-containing anti-malarial combination treatments are not used appropriately. Here, I debate that the best way to manage multidrug resistant malaria is to make best use of existing treatments and to develop new classes of anti-malarial drugs and not to make ‘triple combination therapies’ when there is already resistance to one or more proposed components. |
first_indexed | 2024-04-13T08:38:59Z |
format | Article |
id | doaj.art-67e4387191e5428894934e483a7c8fc7 |
institution | Directory Open Access Journal |
issn | 1475-2875 |
language | English |
last_indexed | 2024-04-13T08:38:59Z |
publishDate | 2019-10-01 |
publisher | BMC |
record_format | Article |
series | Malaria Journal |
spelling | doaj.art-67e4387191e5428894934e483a7c8fc72022-12-22T02:53:58ZengBMCMalaria Journal1475-28752019-10-011811310.1186/s12936-019-2976-7Triple artemisinin-containing combination anti-malarial treatments should be implemented now to delay the emergence of resistance: the case againstSanjeev Krishna0Centre for Diagnostics and Antimicrobial Resistance, Institute for Infection & Immunity, St. George’s, University of LondonAbstract Managing multidrug resistant malaria can be problematic if currently available artemisinin-containing anti-malarial combination treatments are not used appropriately. Here, I debate that the best way to manage multidrug resistant malaria is to make best use of existing treatments and to develop new classes of anti-malarial drugs and not to make ‘triple combination therapies’ when there is already resistance to one or more proposed components.http://link.springer.com/article/10.1186/s12936-019-2976-7 |
spellingShingle | Sanjeev Krishna Triple artemisinin-containing combination anti-malarial treatments should be implemented now to delay the emergence of resistance: the case against Malaria Journal |
title | Triple artemisinin-containing combination anti-malarial treatments should be implemented now to delay the emergence of resistance: the case against |
title_full | Triple artemisinin-containing combination anti-malarial treatments should be implemented now to delay the emergence of resistance: the case against |
title_fullStr | Triple artemisinin-containing combination anti-malarial treatments should be implemented now to delay the emergence of resistance: the case against |
title_full_unstemmed | Triple artemisinin-containing combination anti-malarial treatments should be implemented now to delay the emergence of resistance: the case against |
title_short | Triple artemisinin-containing combination anti-malarial treatments should be implemented now to delay the emergence of resistance: the case against |
title_sort | triple artemisinin containing combination anti malarial treatments should be implemented now to delay the emergence of resistance the case against |
url | http://link.springer.com/article/10.1186/s12936-019-2976-7 |
work_keys_str_mv | AT sanjeevkrishna tripleartemisinincontainingcombinationantimalarialtreatmentsshouldbeimplementednowtodelaytheemergenceofresistancethecaseagainst |