Polysaccharides-Based Injectable Hydrogels: Preparation, Characteristics, and Biomedical Applications
Polysaccharides-based injectable hydrogels are a unique group of biodegradable and biocompatible materials that have shown great potential in the different biomedical fields. The biomolecules or cells can be simply blended with the hydrogel precursors with a high loading capacity by homogenous mixin...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-12-01
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| Series: | Colloids and Interfaces |
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| Online Access: | https://www.mdpi.com/2504-5377/6/4/78 |
| _version_ | 1827641217645543424 |
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| author | Naglaa Salem El-Sayed Samir Kamel |
| author_facet | Naglaa Salem El-Sayed Samir Kamel |
| author_sort | Naglaa Salem El-Sayed |
| collection | DOAJ |
| description | Polysaccharides-based injectable hydrogels are a unique group of biodegradable and biocompatible materials that have shown great potential in the different biomedical fields. The biomolecules or cells can be simply blended with the hydrogel precursors with a high loading capacity by homogenous mixing. The different physical and chemical crosslinking approaches for preparing polysaccharide-based injectable hydrogels are reviewed. Additionally, the review highlights the recent work using polysaccharides-based injectable hydrogels as stimuli-responsive delivery vehicles for the controlled release of different therapeutic agents and viscoelastic matrix for cell encapsulation. Moreover, the application of polysaccharides-based injectable hydrogel in regenerative medicine as tissue scaffold and wound healing dressing is covered. |
| first_indexed | 2024-03-09T17:10:17Z |
| format | Article |
| id | doaj.art-67e658d753f64f50a458365fe256ade1 |
| institution | Directory Open Access Journal |
| issn | 2504-5377 |
| language | English |
| last_indexed | 2024-03-09T17:10:17Z |
| publishDate | 2022-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Colloids and Interfaces |
| spelling | doaj.art-67e658d753f64f50a458365fe256ade12023-11-24T14:06:52ZengMDPI AGColloids and Interfaces2504-53772022-12-01647810.3390/colloids6040078Polysaccharides-Based Injectable Hydrogels: Preparation, Characteristics, and Biomedical ApplicationsNaglaa Salem El-Sayed0Samir Kamel1Cellulose and Paper Department, National Research Centre, Cairo 12622, EgyptCellulose and Paper Department, National Research Centre, Cairo 12622, EgyptPolysaccharides-based injectable hydrogels are a unique group of biodegradable and biocompatible materials that have shown great potential in the different biomedical fields. The biomolecules or cells can be simply blended with the hydrogel precursors with a high loading capacity by homogenous mixing. The different physical and chemical crosslinking approaches for preparing polysaccharide-based injectable hydrogels are reviewed. Additionally, the review highlights the recent work using polysaccharides-based injectable hydrogels as stimuli-responsive delivery vehicles for the controlled release of different therapeutic agents and viscoelastic matrix for cell encapsulation. Moreover, the application of polysaccharides-based injectable hydrogel in regenerative medicine as tissue scaffold and wound healing dressing is covered.https://www.mdpi.com/2504-5377/6/4/78polysaccharidesinjectable hydrogelinjectable mechanismsbiomedical applications |
| spellingShingle | Naglaa Salem El-Sayed Samir Kamel Polysaccharides-Based Injectable Hydrogels: Preparation, Characteristics, and Biomedical Applications Colloids and Interfaces polysaccharides injectable hydrogel injectable mechanisms biomedical applications |
| title | Polysaccharides-Based Injectable Hydrogels: Preparation, Characteristics, and Biomedical Applications |
| title_full | Polysaccharides-Based Injectable Hydrogels: Preparation, Characteristics, and Biomedical Applications |
| title_fullStr | Polysaccharides-Based Injectable Hydrogels: Preparation, Characteristics, and Biomedical Applications |
| title_full_unstemmed | Polysaccharides-Based Injectable Hydrogels: Preparation, Characteristics, and Biomedical Applications |
| title_short | Polysaccharides-Based Injectable Hydrogels: Preparation, Characteristics, and Biomedical Applications |
| title_sort | polysaccharides based injectable hydrogels preparation characteristics and biomedical applications |
| topic | polysaccharides injectable hydrogel injectable mechanisms biomedical applications |
| url | https://www.mdpi.com/2504-5377/6/4/78 |
| work_keys_str_mv | AT naglaasalemelsayed polysaccharidesbasedinjectablehydrogelspreparationcharacteristicsandbiomedicalapplications AT samirkamel polysaccharidesbasedinjectablehydrogelspreparationcharacteristicsandbiomedicalapplications |