Feasibility, complications, and quality of visualization using video capsule endoscopy in 40 dogs with overt or questionable gastrointestinal bleeding

Abstract Background Prospective studies describing video capsule endoscopy (VCE), its feasibility, and complications in dogs are limited. Objective To assess VCE, quality of visualization, complications, and risk factors for incomplete studies in dogs with overt or questionable gastrointestinal blee...

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Main Authors: Jenny Stiller, Alice M. Defarges, Brigitte A. Brisson, Alexa M. E. Bersenas, David L. Pearl
Format: Article
Language:English
Published: Wiley 2021-07-01
Series:Journal of Veterinary Internal Medicine
Subjects:
Online Access:https://doi.org/10.1111/jvim.16153
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author Jenny Stiller
Alice M. Defarges
Brigitte A. Brisson
Alexa M. E. Bersenas
David L. Pearl
author_facet Jenny Stiller
Alice M. Defarges
Brigitte A. Brisson
Alexa M. E. Bersenas
David L. Pearl
author_sort Jenny Stiller
collection DOAJ
description Abstract Background Prospective studies describing video capsule endoscopy (VCE), its feasibility, and complications in dogs are limited. Objective To assess VCE, quality of visualization, complications, and risk factors for incomplete studies in dogs with overt or questionable gastrointestinal bleeding (GIB). Animals Forty dogs with overt or questionable GIB. Methods Prospective, multicenter, interventional study. From August 2017 to March 2020, dogs were examined by VCE (ALICAM) because of overt or questionable GIB. Reported outcomes included diagnostic results of VCE study, quality of visualization, and complications. Risk factors for incomplete studies were evaluated using logistic regression. Results In total, 40 dogs (13 overt, 27 questionable GIB) were included. The capsules were administered PO in 29 and endoscopically in 11 dogs (6 duodenum, 5 stomach). One capsule was not retrieved. In 24 of 39 recordings, bleeding lesions were identified (10 overt GIB, 14 questionable GIB). Overall, the quality of visualization was poor to limited in the stomach and colon, and adequate to good in the small intestine. The most common complication was an incomplete study in 15/39 studies, particularly after oral administration (13/28). Risk factors for incomplete study after oral administration included administration of simethicone or opioids, chronic enteropathy, and capsule gastric transit time >6 hours. Conclusions and Clinical Importance Video capsule endoscopy can be used to diagnose a variety of lesions causing bleeding in the gastrointestinal tract of dogs with questionable GIB. Incomplete studies are the most common complications in dogs after oral administration of capsules.
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spelling doaj.art-67e8dfd6b382436297bd33f73f870fb82022-12-21T22:52:37ZengWileyJournal of Veterinary Internal Medicine0891-66401939-16762021-07-013541743175310.1111/jvim.16153Feasibility, complications, and quality of visualization using video capsule endoscopy in 40 dogs with overt or questionable gastrointestinal bleedingJenny Stiller0Alice M. Defarges1Brigitte A. Brisson2Alexa M. E. Bersenas3David L. Pearl4Department of Clinical Studies Ontario Veterinary College, University of Guelph Guelph Ontario CanadaDepartment of Clinical Studies Ontario Veterinary College, University of Guelph Guelph Ontario CanadaDepartment of Clinical Studies Ontario Veterinary College, University of Guelph Guelph Ontario CanadaDepartment of Clinical Studies Ontario Veterinary College, University of Guelph Guelph Ontario CanadaDepartment of Population Medicine Ontario Veterinary College, University of Guelph Guelph Ontario CanadaAbstract Background Prospective studies describing video capsule endoscopy (VCE), its feasibility, and complications in dogs are limited. Objective To assess VCE, quality of visualization, complications, and risk factors for incomplete studies in dogs with overt or questionable gastrointestinal bleeding (GIB). Animals Forty dogs with overt or questionable GIB. Methods Prospective, multicenter, interventional study. From August 2017 to March 2020, dogs were examined by VCE (ALICAM) because of overt or questionable GIB. Reported outcomes included diagnostic results of VCE study, quality of visualization, and complications. Risk factors for incomplete studies were evaluated using logistic regression. Results In total, 40 dogs (13 overt, 27 questionable GIB) were included. The capsules were administered PO in 29 and endoscopically in 11 dogs (6 duodenum, 5 stomach). One capsule was not retrieved. In 24 of 39 recordings, bleeding lesions were identified (10 overt GIB, 14 questionable GIB). Overall, the quality of visualization was poor to limited in the stomach and colon, and adequate to good in the small intestine. The most common complication was an incomplete study in 15/39 studies, particularly after oral administration (13/28). Risk factors for incomplete study after oral administration included administration of simethicone or opioids, chronic enteropathy, and capsule gastric transit time >6 hours. Conclusions and Clinical Importance Video capsule endoscopy can be used to diagnose a variety of lesions causing bleeding in the gastrointestinal tract of dogs with questionable GIB. Incomplete studies are the most common complications in dogs after oral administration of capsules.https://doi.org/10.1111/jvim.16153anemiacaninegastroenterologyhemorrhagesimethicone
spellingShingle Jenny Stiller
Alice M. Defarges
Brigitte A. Brisson
Alexa M. E. Bersenas
David L. Pearl
Feasibility, complications, and quality of visualization using video capsule endoscopy in 40 dogs with overt or questionable gastrointestinal bleeding
Journal of Veterinary Internal Medicine
anemia
canine
gastroenterology
hemorrhage
simethicone
title Feasibility, complications, and quality of visualization using video capsule endoscopy in 40 dogs with overt or questionable gastrointestinal bleeding
title_full Feasibility, complications, and quality of visualization using video capsule endoscopy in 40 dogs with overt or questionable gastrointestinal bleeding
title_fullStr Feasibility, complications, and quality of visualization using video capsule endoscopy in 40 dogs with overt or questionable gastrointestinal bleeding
title_full_unstemmed Feasibility, complications, and quality of visualization using video capsule endoscopy in 40 dogs with overt or questionable gastrointestinal bleeding
title_short Feasibility, complications, and quality of visualization using video capsule endoscopy in 40 dogs with overt or questionable gastrointestinal bleeding
title_sort feasibility complications and quality of visualization using video capsule endoscopy in 40 dogs with overt or questionable gastrointestinal bleeding
topic anemia
canine
gastroenterology
hemorrhage
simethicone
url https://doi.org/10.1111/jvim.16153
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