Cucurbitacin E induces cell cycle G2/M phase arrest and apoptosis in triple negative breast cancer.

Cucurbitacin E induces cell cycle G2/M phase arrest and apoptosis in triple negative breast cancer.

Triple negative breast cancer (TNBC) is a highly aggressive form of breast cancer resistant to many common treatments. In this study, we compared the effects of 12 phytochemical drugs on four cancer cell lines, and noticed that Cucurbitacin E (CuE) significantly inhibited TNBC cell growth by inducin...

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Bibliographic Details
Main Authors:	Yanjie Kong, Jianchao Chen, Zhongmei Zhou, Houjun Xia, Ming-Hua Qiu, Ceshi Chen
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2014-01-01
Series:	PLoS ONE
Online Access:	http://europepmc.org/articles/PMC4114842?pdf=render

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