Biomaterials derived from hard palate mucosa for tissue engineering and regenerative medicine
Autologous materials have superior biosafety and are widely used in clinical practice. Due to its excellent trauma-healing ability, the hard palate mucosa (HPM) has become a hot spot for autologous donor area research. Multiple studies have conducted an in-depth analysis of the healing ability of th...
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| Format: | Article |
| Language: | English |
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Elsevier
2023-10-01
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| Series: | Materials Today Bio |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2590006423001941 |
| _version_ | 1797682464833929216 |
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| author | Lingfei Ren Zhiwei Jiang Hui Zhang Yani Chen Danji Zhu Jin He Yunxuan Chen Ying Wang Guoli Yang |
| author_facet | Lingfei Ren Zhiwei Jiang Hui Zhang Yani Chen Danji Zhu Jin He Yunxuan Chen Ying Wang Guoli Yang |
| author_sort | Lingfei Ren |
| collection | DOAJ |
| description | Autologous materials have superior biosafety and are widely used in clinical practice. Due to its excellent trauma-healing ability, the hard palate mucosa (HPM) has become a hot spot for autologous donor area research. Multiple studies have conducted an in-depth analysis of the healing ability of the HPM at the cellular and molecular levels. In addition, the HPM has good maneuverability as a donor area for soft tissue grafts, and researchers have isolated various specific mesenchymal stem cells (MSCs) from HPM. Free soft tissue grafts obtained from the HPM have been widely used in the clinic and have played an essential role in dentistry, eyelid reconstruction, and the repair of other specific soft tissue defects. This article reviews the advantages of HPM as a donor area and its related mechanisms, classes of HPM-derived biomaterials, the current status of clinical applications, challenges, and future development directions. |
| first_indexed | 2024-03-12T00:01:04Z |
| format | Article |
| id | doaj.art-67ef57ea9d7a4bd588a08f62fe9cda2e |
| institution | Directory Open Access Journal |
| issn | 2590-0064 |
| language | English |
| last_indexed | 2024-03-12T00:01:04Z |
| publishDate | 2023-10-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Materials Today Bio |
| spelling | doaj.art-67ef57ea9d7a4bd588a08f62fe9cda2e2023-09-18T04:30:13ZengElsevierMaterials Today Bio2590-00642023-10-0122100734Biomaterials derived from hard palate mucosa for tissue engineering and regenerative medicineLingfei Ren0Zhiwei Jiang1Hui Zhang2Yani Chen3Danji Zhu4Jin He5Yunxuan Chen6Ying Wang7Guoli Yang8Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Zhejiang Provincial Clinical Research Center for Oral Diseases, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Cancer Center of Zhejiang University, Engineering Research Center of Oral Biomaterials and Devices of Zhejiang Province, Hangzhou, 310000, ChinaStomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Zhejiang Provincial Clinical Research Center for Oral Diseases, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Cancer Center of Zhejiang University, Engineering Research Center of Oral Biomaterials and Devices of Zhejiang Province, Hangzhou, 310000, ChinaStomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Zhejiang Provincial Clinical Research Center for Oral Diseases, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Cancer Center of Zhejiang University, Engineering Research Center of Oral Biomaterials and Devices of Zhejiang Province, Hangzhou, 310000, ChinaStomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Zhejiang Provincial Clinical Research Center for Oral Diseases, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Cancer Center of Zhejiang University, Engineering Research Center of Oral Biomaterials and Devices of Zhejiang Province, Hangzhou, 310000, ChinaStomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Zhejiang Provincial Clinical Research Center for Oral Diseases, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Cancer Center of Zhejiang University, Engineering Research Center of Oral Biomaterials and Devices of Zhejiang Province, Hangzhou, 310000, ChinaStomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Zhejiang Provincial Clinical Research Center for Oral Diseases, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Cancer Center of Zhejiang University, Engineering Research Center of Oral Biomaterials and Devices of Zhejiang Province, Hangzhou, 310000, ChinaStomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Zhejiang Provincial Clinical Research Center for Oral Diseases, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Cancer Center of Zhejiang University, Engineering Research Center of Oral Biomaterials and Devices of Zhejiang Province, Hangzhou, 310000, ChinaCorresponding author.; Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Zhejiang Provincial Clinical Research Center for Oral Diseases, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Cancer Center of Zhejiang University, Engineering Research Center of Oral Biomaterials and Devices of Zhejiang Province, Hangzhou, 310000, ChinaCorresponding author.; Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Zhejiang Provincial Clinical Research Center for Oral Diseases, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Cancer Center of Zhejiang University, Engineering Research Center of Oral Biomaterials and Devices of Zhejiang Province, Hangzhou, 310000, ChinaAutologous materials have superior biosafety and are widely used in clinical practice. Due to its excellent trauma-healing ability, the hard palate mucosa (HPM) has become a hot spot for autologous donor area research. Multiple studies have conducted an in-depth analysis of the healing ability of the HPM at the cellular and molecular levels. In addition, the HPM has good maneuverability as a donor area for soft tissue grafts, and researchers have isolated various specific mesenchymal stem cells (MSCs) from HPM. Free soft tissue grafts obtained from the HPM have been widely used in the clinic and have played an essential role in dentistry, eyelid reconstruction, and the repair of other specific soft tissue defects. This article reviews the advantages of HPM as a donor area and its related mechanisms, classes of HPM-derived biomaterials, the current status of clinical applications, challenges, and future development directions.http://www.sciencedirect.com/science/article/pii/S2590006423001941Autologous biomaterialsHard palate mucosaTissue engineeringRegenerative medicine |
| spellingShingle | Lingfei Ren Zhiwei Jiang Hui Zhang Yani Chen Danji Zhu Jin He Yunxuan Chen Ying Wang Guoli Yang Biomaterials derived from hard palate mucosa for tissue engineering and regenerative medicine Materials Today Bio Autologous biomaterials Hard palate mucosa Tissue engineering Regenerative medicine |
| title | Biomaterials derived from hard palate mucosa for tissue engineering and regenerative medicine |
| title_full | Biomaterials derived from hard palate mucosa for tissue engineering and regenerative medicine |
| title_fullStr | Biomaterials derived from hard palate mucosa for tissue engineering and regenerative medicine |
| title_full_unstemmed | Biomaterials derived from hard palate mucosa for tissue engineering and regenerative medicine |
| title_short | Biomaterials derived from hard palate mucosa for tissue engineering and regenerative medicine |
| title_sort | biomaterials derived from hard palate mucosa for tissue engineering and regenerative medicine |
| topic | Autologous biomaterials Hard palate mucosa Tissue engineering Regenerative medicine |
| url | http://www.sciencedirect.com/science/article/pii/S2590006423001941 |
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