Effect of PRP on retinal blood circulation time and hemodynamics in patients with DR
AIM: To analyze the effect of pan-retinal photocoagulation(PRP)surgery on retinal arteriovenous circulation time and hemodynamics in patients with diabetic retinopathy(DR), and provide reference for clinical treatment. <p>METHODS: Eighty patients with DR who underwent PRP treatment in our hosp...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Press of International Journal of Ophthalmology (IJO PRESS)
2018-11-01
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| Series: | Guoji Yanke Zazhi |
| Subjects: | |
| Online Access: | http://ies.ijo.cn/cn_publish/2018/11/201811022.pdf |
| _version_ | 1819072172432293888 |
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| author | Yi-Yi Wen Dong-Hao Li Guan-Feng Wang Qian Yang Chen |
| author_facet | Yi-Yi Wen Dong-Hao Li Guan-Feng Wang Qian Yang Chen |
| author_sort | Yi-Yi Wen |
| collection | DOAJ |
| description | AIM: To analyze the effect of pan-retinal photocoagulation(PRP)surgery on retinal arteriovenous circulation time and hemodynamics in patients with diabetic retinopathy(DR), and provide reference for clinical treatment. <p>METHODS: Eighty patients with DR who underwent PRP treatment in our hospital during May 2013 to February 2018 were selected for 80 eyes. The fundus fluorescein angiography system was used to record laminar flow time and total filling time(V1 and V2), retinal artery branch trunk development time and total filling time(A1 and A2), respectively, before and after treatment. Retinal arteriovenous passage time(V2-A1), retinal artery transit time(A2-A1), retinal vein transit time(V2-V1)and retinal capillary passage time(V1-A2)were recorded; we used automatic biochemical analyzer to detect red blood cells aggregation index, hematocrit, plasma viscosity, whole blood viscosity, high shear and low shear viscosity of whole blood; color Doppler ultrasound was used to record ophthalmic artery resistance index(the RI), peak systolic velocity(PSV)and diastolic the end of the flow velocity(EDV). <p>RESULTS: At 3mo after treatment, the V1-A2 time of this group was significantly longer than that before treatment. The red blood cell aggregation index, hematocrit, plasma viscosity, high blood viscosity and low blood viscosity were significantly lower than before treatment. RI was significantly lower than before treatment. EDV and PSV were significantly higher than before treatment, and the difference was statistically significant(<i>P</i><0.05). <p>CONCLUSION: PRP surgery has a certain effect on the retinal arteriovenous circulation time and hemodynamics in patients with DR, and has a significant effect on the transit time of retinal capillaries. |
| first_indexed | 2024-12-21T17:33:30Z |
| format | Article |
| id | doaj.art-67f2f454995b4891b59d06f65e5e0eb1 |
| institution | Directory Open Access Journal |
| issn | 1672-5123 1672-5123 |
| language | English |
| last_indexed | 2024-12-21T17:33:30Z |
| publishDate | 2018-11-01 |
| publisher | Press of International Journal of Ophthalmology (IJO PRESS) |
| record_format | Article |
| series | Guoji Yanke Zazhi |
| spelling | doaj.art-67f2f454995b4891b59d06f65e5e0eb12022-12-21T18:55:50ZengPress of International Journal of Ophthalmology (IJO PRESS)Guoji Yanke Zazhi1672-51231672-51232018-11-0118112039204110.3980/j.issn.1672-5123.2018.11.22Effect of PRP on retinal blood circulation time and hemodynamics in patients with DRYi-Yi Wen0Dong-Hao Li1Guan-Feng Wang2Qian Yang3Chen4Department of Ophthalmology, the Third Affiliated Hospital of Guangzhou Medical University, Guangzhou 510150, Guangdong Province, ChinaDepartment of Ophthalmology, the Third Affiliated Hospital of Guangzhou Medical University, Guangzhou 510150, Guangdong Province, ChinaDepartment of Ophthalmology, the Third Affiliated Hospital of Guangzhou Medical University, Guangzhou 510150, Guangdong Province, ChinaDepartment of Ophthalmology, The First People's Hospital of Longquanyi District, Chengdu 610100, Sichuan Province, ChinaDepartment of Ophthalmology, Yiyang Central Hospital, Yiyang 413000, Hunan Province, ChinaAIM: To analyze the effect of pan-retinal photocoagulation(PRP)surgery on retinal arteriovenous circulation time and hemodynamics in patients with diabetic retinopathy(DR), and provide reference for clinical treatment. <p>METHODS: Eighty patients with DR who underwent PRP treatment in our hospital during May 2013 to February 2018 were selected for 80 eyes. The fundus fluorescein angiography system was used to record laminar flow time and total filling time(V1 and V2), retinal artery branch trunk development time and total filling time(A1 and A2), respectively, before and after treatment. Retinal arteriovenous passage time(V2-A1), retinal artery transit time(A2-A1), retinal vein transit time(V2-V1)and retinal capillary passage time(V1-A2)were recorded; we used automatic biochemical analyzer to detect red blood cells aggregation index, hematocrit, plasma viscosity, whole blood viscosity, high shear and low shear viscosity of whole blood; color Doppler ultrasound was used to record ophthalmic artery resistance index(the RI), peak systolic velocity(PSV)and diastolic the end of the flow velocity(EDV). <p>RESULTS: At 3mo after treatment, the V1-A2 time of this group was significantly longer than that before treatment. The red blood cell aggregation index, hematocrit, plasma viscosity, high blood viscosity and low blood viscosity were significantly lower than before treatment. RI was significantly lower than before treatment. EDV and PSV were significantly higher than before treatment, and the difference was statistically significant(<i>P</i><0.05). <p>CONCLUSION: PRP surgery has a certain effect on the retinal arteriovenous circulation time and hemodynamics in patients with DR, and has a significant effect on the transit time of retinal capillaries.http://ies.ijo.cn/cn_publish/2018/11/201811022.pdfdiabetic retinopathypanretinal photocoagulationhemodynamics |
| spellingShingle | Yi-Yi Wen Dong-Hao Li Guan-Feng Wang Qian Yang Chen Effect of PRP on retinal blood circulation time and hemodynamics in patients with DR Guoji Yanke Zazhi diabetic retinopathy panretinal photocoagulation hemodynamics |
| title | Effect of PRP on retinal blood circulation time and hemodynamics in patients with DR |
| title_full | Effect of PRP on retinal blood circulation time and hemodynamics in patients with DR |
| title_fullStr | Effect of PRP on retinal blood circulation time and hemodynamics in patients with DR |
| title_full_unstemmed | Effect of PRP on retinal blood circulation time and hemodynamics in patients with DR |
| title_short | Effect of PRP on retinal blood circulation time and hemodynamics in patients with DR |
| title_sort | effect of prp on retinal blood circulation time and hemodynamics in patients with dr |
| topic | diabetic retinopathy panretinal photocoagulation hemodynamics |
| url | http://ies.ijo.cn/cn_publish/2018/11/201811022.pdf |
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