An Update on the Effectiveness of Probiotics in the Prevention and Treatment of Cancer
Probiotics are living microbes that play a significant role in protecting the host in various ways. Gut microbiota is one of the key players in maintaining homeostasis. Cancer is considered one of the most significant causes of death worldwide. Although cancer treatment has received much attention i...
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MDPI AG
2022-01-01
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| Series: | Life |
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| Online Access: | https://www.mdpi.com/2075-1729/12/1/59 |
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| author | Vidya Sankarapandian Balu Alagar Venmathi Maran Ramya Lakshmi Rajendran Manasi P. Jogalekar Sridharan Gurunagarajan Rajapandiyan Krishnamoorthy Prakash Gangadaran Byeong-Cheol Ahn |
| author_facet | Vidya Sankarapandian Balu Alagar Venmathi Maran Ramya Lakshmi Rajendran Manasi P. Jogalekar Sridharan Gurunagarajan Rajapandiyan Krishnamoorthy Prakash Gangadaran Byeong-Cheol Ahn |
| author_sort | Vidya Sankarapandian |
| collection | DOAJ |
| description | Probiotics are living microbes that play a significant role in protecting the host in various ways. Gut microbiota is one of the key players in maintaining homeostasis. Cancer is considered one of the most significant causes of death worldwide. Although cancer treatment has received much attention in recent years, the number of people suffering from neoplastic syndrome continues to increase. Despite notable improvements in the field of cancer therapy, tackling cancer has been challenging due to the multiple properties of cancer cells and their ability to evade the immune system. Probiotics alter the immunological and cellular responses by enhancing the epithelial barrier and stimulating the production of anti-inflammatory, antioxidant, and anticarcinogenic compounds, thereby reducing cancer burden and growth. The present review focuses on the various mechanisms underlying the role of probiotics in the prevention and treatment of cancer. |
| first_indexed | 2024-03-10T01:07:24Z |
| format | Article |
| id | doaj.art-67f3a786f5b64302a3d538c7318a271a |
| institution | Directory Open Access Journal |
| issn | 2075-1729 |
| language | English |
| last_indexed | 2024-03-10T01:07:24Z |
| publishDate | 2022-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Life |
| spelling | doaj.art-67f3a786f5b64302a3d538c7318a271a2023-11-23T14:24:18ZengMDPI AGLife2075-17292022-01-011215910.3390/life12010059An Update on the Effectiveness of Probiotics in the Prevention and Treatment of CancerVidya Sankarapandian0Balu Alagar Venmathi Maran1Ramya Lakshmi Rajendran2Manasi P. Jogalekar3Sridharan Gurunagarajan4Rajapandiyan Krishnamoorthy5Prakash Gangadaran6Byeong-Cheol Ahn7Department of Microbiology, Srimad Andavan Arts and Science College, Bharathidasan University, Trichy 620005, IndiaBorneo Marine Research Institute, Universiti Malaysia Sabah, Kota Kinabalu 88400, MalaysiaDepartment of Nuclear Medicine, School of Medicine, Kyungpook National University, Daegu 41944, KoreaHelen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, CA 94158, USADepartment of Biochemistry, Srimad Andavan Arts and Science College, Bharathidasan University, Trichy 620005, IndiaNanobiotechnology and Molecular Biology Research Lab, Department of Food Science and Nutrition, College of Food and Agriculture Sciences, King Saud University, Riyadh 4545, Saudi ArabiaDepartment of Nuclear Medicine, School of Medicine, Kyungpook National University, Daegu 41944, KoreaDepartment of Nuclear Medicine, School of Medicine, Kyungpook National University, Daegu 41944, KoreaProbiotics are living microbes that play a significant role in protecting the host in various ways. Gut microbiota is one of the key players in maintaining homeostasis. Cancer is considered one of the most significant causes of death worldwide. Although cancer treatment has received much attention in recent years, the number of people suffering from neoplastic syndrome continues to increase. Despite notable improvements in the field of cancer therapy, tackling cancer has been challenging due to the multiple properties of cancer cells and their ability to evade the immune system. Probiotics alter the immunological and cellular responses by enhancing the epithelial barrier and stimulating the production of anti-inflammatory, antioxidant, and anticarcinogenic compounds, thereby reducing cancer burden and growth. The present review focuses on the various mechanisms underlying the role of probiotics in the prevention and treatment of cancer.https://www.mdpi.com/2075-1729/12/1/59probioticsimmunomodulationmetastasisbiotherapyoncogene kinase |
| spellingShingle | Vidya Sankarapandian Balu Alagar Venmathi Maran Ramya Lakshmi Rajendran Manasi P. Jogalekar Sridharan Gurunagarajan Rajapandiyan Krishnamoorthy Prakash Gangadaran Byeong-Cheol Ahn An Update on the Effectiveness of Probiotics in the Prevention and Treatment of Cancer Life probiotics immunomodulation metastasis biotherapy oncogene kinase |
| title | An Update on the Effectiveness of Probiotics in the Prevention and Treatment of Cancer |
| title_full | An Update on the Effectiveness of Probiotics in the Prevention and Treatment of Cancer |
| title_fullStr | An Update on the Effectiveness of Probiotics in the Prevention and Treatment of Cancer |
| title_full_unstemmed | An Update on the Effectiveness of Probiotics in the Prevention and Treatment of Cancer |
| title_short | An Update on the Effectiveness of Probiotics in the Prevention and Treatment of Cancer |
| title_sort | update on the effectiveness of probiotics in the prevention and treatment of cancer |
| topic | probiotics immunomodulation metastasis biotherapy oncogene kinase |
| url | https://www.mdpi.com/2075-1729/12/1/59 |
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