Analysis of Salivary Levels of IL-8 and IL-34 in Periodontitis Patients: An Analytical Cross-Sectional Study
Introduction: The aim of this study was to determine the salivary levels of interleukin-8 (IL-8) and interleukin-34 (IL-34) among patients with periodontitis and healthy individuals. Methods: Thirty participants with periodontitis and 30 healthy individuals were enrolled in this study. Enzyme-linked...
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| Formato: | Artigo |
| Idioma: | English |
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Wolters Kluwer Medknow Publications
2023-01-01
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| Colecção: | Dental Hypotheses |
| Assuntos: | |
| Acesso em linha: | http://www.dentalhypotheses.com/article.asp?issn=2155-8213;year=2023;volume=14;issue=4;spage=100;epage=102;aulast=Abood |
| _version_ | 1827270113437417472 |
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| author | Farah R Abood Zainab A Aldhaher |
| author_facet | Farah R Abood Zainab A Aldhaher |
| author_sort | Farah R Abood |
| collection | DOAJ |
| description | Introduction: The aim of this study was to determine the salivary levels of interleukin-8 (IL-8) and interleukin-34 (IL-34) among patients with periodontitis and healthy individuals. Methods: Thirty participants with periodontitis and 30 healthy individuals were enrolled in this study. Enzyme-linked immunosorbent assay (ELISA) was used to determine salivary levels of IL-8 and IL-34, blindly. Statistical analysis was carried out by unequal variances t-test (Welch’s t-test) and the Pearson correlation coefficient using R software. Result: Statistically significant differences were found between participants with periodontitis and healthy subjects regarding salivary levels of IL-8 (P = 0.012) and IL-34 (P < 0.001). There was a non-significant (P > 0.05) correlation between salivary levels of IL-8 and IL-34 and periodontal parameters, including plaque index, bleeding on probing, probing pocket depth, and clinical attachment loss. Conclusion: Within the limitations of this study, the salivary levels of IL-8 and IL-34 were higher among participants with periodontitis in comparison with healthy subjects. In the periodontitis group, salivary levels of IL-8 and IL-34 were not correlated with clinical indicators of periodontitis. |
| first_indexed | 2024-03-08T13:12:16Z |
| format | Article |
| id | doaj.art-67f939c87c2140fb8000d3dad054a3f7 |
| institution | Directory Open Access Journal |
| issn | 2155-8213 |
| language | English |
| last_indexed | 2025-03-22T05:16:16Z |
| publishDate | 2023-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Dental Hypotheses |
| spelling | doaj.art-67f939c87c2140fb8000d3dad054a3f72024-04-27T04:54:08ZengWolters Kluwer Medknow PublicationsDental Hypotheses2155-82132023-01-0114410010210.4103/denthyp.denthyp_63_23Analysis of Salivary Levels of IL-8 and IL-34 in Periodontitis Patients: An Analytical Cross-Sectional StudyFarah R AboodZainab A AldhaherIntroduction: The aim of this study was to determine the salivary levels of interleukin-8 (IL-8) and interleukin-34 (IL-34) among patients with periodontitis and healthy individuals. Methods: Thirty participants with periodontitis and 30 healthy individuals were enrolled in this study. Enzyme-linked immunosorbent assay (ELISA) was used to determine salivary levels of IL-8 and IL-34, blindly. Statistical analysis was carried out by unequal variances t-test (Welch’s t-test) and the Pearson correlation coefficient using R software. Result: Statistically significant differences were found between participants with periodontitis and healthy subjects regarding salivary levels of IL-8 (P = 0.012) and IL-34 (P < 0.001). There was a non-significant (P > 0.05) correlation between salivary levels of IL-8 and IL-34 and periodontal parameters, including plaque index, bleeding on probing, probing pocket depth, and clinical attachment loss. Conclusion: Within the limitations of this study, the salivary levels of IL-8 and IL-34 were higher among participants with periodontitis in comparison with healthy subjects. In the periodontitis group, salivary levels of IL-8 and IL-34 were not correlated with clinical indicators of periodontitis.http://www.dentalhypotheses.com/article.asp?issn=2155-8213;year=2023;volume=14;issue=4;spage=100;epage=102;aulast=Aboodelisainterleukin-8interleukin-34periodontitisperiodontal diseasesalivary biomarkerssaliva |
| spellingShingle | Farah R Abood Zainab A Aldhaher Analysis of Salivary Levels of IL-8 and IL-34 in Periodontitis Patients: An Analytical Cross-Sectional Study Dental Hypotheses elisa interleukin-8 interleukin-34 periodontitis periodontal disease salivary biomarkers saliva |
| title | Analysis of Salivary Levels of IL-8 and IL-34 in Periodontitis Patients: An Analytical Cross-Sectional Study |
| title_full | Analysis of Salivary Levels of IL-8 and IL-34 in Periodontitis Patients: An Analytical Cross-Sectional Study |
| title_fullStr | Analysis of Salivary Levels of IL-8 and IL-34 in Periodontitis Patients: An Analytical Cross-Sectional Study |
| title_full_unstemmed | Analysis of Salivary Levels of IL-8 and IL-34 in Periodontitis Patients: An Analytical Cross-Sectional Study |
| title_short | Analysis of Salivary Levels of IL-8 and IL-34 in Periodontitis Patients: An Analytical Cross-Sectional Study |
| title_sort | analysis of salivary levels of il 8 and il 34 in periodontitis patients an analytical cross sectional study |
| topic | elisa interleukin-8 interleukin-34 periodontitis periodontal disease salivary biomarkers saliva |
| url | http://www.dentalhypotheses.com/article.asp?issn=2155-8213;year=2023;volume=14;issue=4;spage=100;epage=102;aulast=Abood |
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