Prolyl Isomerase Pin1 Regulates the Stability of Hepatitis B Virus Core Protein

Prolyl Isomerase Pin1 Regulates the Stability of Hepatitis B Virus Core Protein

The dynamic interplay between virus and host proteins is critical for establishing efficient viral replication and virus-induced pathogenesis. Phosphorylation-dependent prolyl isomerization by Pin1 provides a unique mechanism of molecular switching to control both protein function and stability. We...

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Bibliographic Details
Main Authors: Mayuko Nishi, Kei Miyakawa, Satoko Matsunaga, Hajera Khatun, Yutaro Yamaoka, Koichi Watashi, Masaya Sugiyama, Hirokazu Kimura, Takaji Wakita, Akihide Ryo
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
virus-host interaction
phosphorylation
prolyl isomerization
lysosome
hepatitis B virus
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2020.00026/full

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