Exploring the degradation behavior of MgXAg alloys by in vitro electrochemical methods
Magnesium as biodegradable biomaterial could serve as bone augmentation material in implant dentistry. The knowledge about the predictability of the biodegradation process is essential as this process needs to go hand in hand with the formation of new bone to gradually replace the augmentation mater...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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KeAi Communications Co., Ltd.
2022-01-01
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| Series: | Bioactive Materials |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2452199X21002644 |
| _version_ | 1797204463699623936 |
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| author | Yuqiuhan Zhang Tycho Zimmermann Wolf-Dieter Mueller Frank Witte Florian Beuer Andreas Schwitalla |
| author_facet | Yuqiuhan Zhang Tycho Zimmermann Wolf-Dieter Mueller Frank Witte Florian Beuer Andreas Schwitalla |
| author_sort | Yuqiuhan Zhang |
| collection | DOAJ |
| description | Magnesium as biodegradable biomaterial could serve as bone augmentation material in implant dentistry. The knowledge about the predictability of the biodegradation process is essential as this process needs to go hand in hand with the formation of new bone to gradually replace the augmentation material. Therefore, this work aimed to assess if the electrochemistry (EC) measurements of the corrosion process correlate with the surface features at various time points during the surface degradation, in order to describe the degradation process of Mg and Mg alloys more reliably, under the assumption that differences in EC behavior can be detected and related to specific patterns on the surface.In this test setup, a special optical chamber was used for electrochemical measurements on Mg and Mg-alloys (Mg2Ag, Mg4Ag, and Mg6Ag). Specimens were investigated using different circulating cell culture solutions as electrolytes, these were minimum essential medium (MEM), Hank's Balanced Salt Solution (HBSS), and MEM+ (MEM with added sodium hydrogen carbonate) at 37 °C. Open circuit potential measurements (OCP) over 30 min followed by cyclic polarization were performed. The electrochemistry data, including OCP, exchange current density and corrosion potential, were compared with visible changes at the surface during these treatments over time. The results show that the addition of silver (Ag) leads to a “standardization” of the degradation regardless of the selected test medium. It is currently difficult to correlate the visible microscopic changes with the data taken from the measurements. Therefore, further investigations are necessary. |
| first_indexed | 2024-04-24T08:35:38Z |
| format | Article |
| id | doaj.art-67fd37767c5f40e8b05ec14c9b442b84 |
| institution | Directory Open Access Journal |
| issn | 2452-199X |
| language | English |
| last_indexed | 2024-04-24T08:35:38Z |
| publishDate | 2022-01-01 |
| publisher | KeAi Communications Co., Ltd. |
| record_format | Article |
| series | Bioactive Materials |
| spelling | doaj.art-67fd37767c5f40e8b05ec14c9b442b842024-04-16T17:17:11ZengKeAi Communications Co., Ltd.Bioactive Materials2452-199X2022-01-017441452Exploring the degradation behavior of MgXAg alloys by in vitro electrochemical methodsYuqiuhan Zhang0Tycho Zimmermann1Wolf-Dieter Mueller2Frank Witte3Florian Beuer4Andreas Schwitalla5Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Dental Materials and Biomaterial Research, Department of Prosthodontics, Geriatric Dentistry and Craniomandibular Disorders, Aßmannshauser Str. 4-6, 14197, Berlin, GermanyCharité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Dental Materials and Biomaterial Research, Department of Prosthodontics, Geriatric Dentistry and Craniomandibular Disorders, Aßmannshauser Str. 4-6, 14197, Berlin, GermanyCorresponding author.; Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Dental Materials and Biomaterial Research, Department of Prosthodontics, Geriatric Dentistry and Craniomandibular Disorders, Aßmannshauser Str. 4-6, 14197, Berlin, GermanyCharité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Dental Materials and Biomaterial Research, Department of Prosthodontics, Geriatric Dentistry and Craniomandibular Disorders, Aßmannshauser Str. 4-6, 14197, Berlin, GermanyCharité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Dental Materials and Biomaterial Research, Department of Prosthodontics, Geriatric Dentistry and Craniomandibular Disorders, Aßmannshauser Str. 4-6, 14197, Berlin, GermanyCharité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Dental Materials and Biomaterial Research, Department of Prosthodontics, Geriatric Dentistry and Craniomandibular Disorders, Aßmannshauser Str. 4-6, 14197, Berlin, GermanyMagnesium as biodegradable biomaterial could serve as bone augmentation material in implant dentistry. The knowledge about the predictability of the biodegradation process is essential as this process needs to go hand in hand with the formation of new bone to gradually replace the augmentation material. Therefore, this work aimed to assess if the electrochemistry (EC) measurements of the corrosion process correlate with the surface features at various time points during the surface degradation, in order to describe the degradation process of Mg and Mg alloys more reliably, under the assumption that differences in EC behavior can be detected and related to specific patterns on the surface.In this test setup, a special optical chamber was used for electrochemical measurements on Mg and Mg-alloys (Mg2Ag, Mg4Ag, and Mg6Ag). Specimens were investigated using different circulating cell culture solutions as electrolytes, these were minimum essential medium (MEM), Hank's Balanced Salt Solution (HBSS), and MEM+ (MEM with added sodium hydrogen carbonate) at 37 °C. Open circuit potential measurements (OCP) over 30 min followed by cyclic polarization were performed. The electrochemistry data, including OCP, exchange current density and corrosion potential, were compared with visible changes at the surface during these treatments over time. The results show that the addition of silver (Ag) leads to a “standardization” of the degradation regardless of the selected test medium. It is currently difficult to correlate the visible microscopic changes with the data taken from the measurements. Therefore, further investigations are necessary.http://www.sciencedirect.com/science/article/pii/S2452199X21002644Biodegradable magnesiumMagnesium silver alloysElectrochemistryHydrogen evolution |
| spellingShingle | Yuqiuhan Zhang Tycho Zimmermann Wolf-Dieter Mueller Frank Witte Florian Beuer Andreas Schwitalla Exploring the degradation behavior of MgXAg alloys by in vitro electrochemical methods Bioactive Materials Biodegradable magnesium Magnesium silver alloys Electrochemistry Hydrogen evolution |
| title | Exploring the degradation behavior of MgXAg alloys by in vitro electrochemical methods |
| title_full | Exploring the degradation behavior of MgXAg alloys by in vitro electrochemical methods |
| title_fullStr | Exploring the degradation behavior of MgXAg alloys by in vitro electrochemical methods |
| title_full_unstemmed | Exploring the degradation behavior of MgXAg alloys by in vitro electrochemical methods |
| title_short | Exploring the degradation behavior of MgXAg alloys by in vitro electrochemical methods |
| title_sort | exploring the degradation behavior of mgxag alloys by in vitro electrochemical methods |
| topic | Biodegradable magnesium Magnesium silver alloys Electrochemistry Hydrogen evolution |
| url | http://www.sciencedirect.com/science/article/pii/S2452199X21002644 |
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