High-Speed Manipulation of Microobjects Using an Automated Two-Fingered Microhand for 3D Microassembly
To assemble microobjects including biological cells quickly and precisely, a fully automated pick-and-place operation is applied. In micromanipulation in liquid, the challenges include strong adhesion forces and high dynamic viscosity. To solve these problems, a reliable manipulation system and spec...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2020-05-01
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| Series: | Micromachines |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2072-666X/11/5/534 |
| _version_ | 1797567159148216320 |
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| author | Eunhye Kim Masaru Kojima Yasushi Mae Tatsuo Arai |
| author_facet | Eunhye Kim Masaru Kojima Yasushi Mae Tatsuo Arai |
| author_sort | Eunhye Kim |
| collection | DOAJ |
| description | To assemble microobjects including biological cells quickly and precisely, a fully automated pick-and-place operation is applied. In micromanipulation in liquid, the challenges include strong adhesion forces and high dynamic viscosity. To solve these problems, a reliable manipulation system and special releasing techniques are indispensable. A microhand having dexterous motion is utilized to grasp an object stably, and an automated stage transports the object quickly. To detach the object adhered to one of the end effectors, two releasing methods—local stream and a dynamic releasing—are utilized. A system using vision-based techniques for the recognition of two fingertips and an object, as well automated releasing methods, can increase the manipulation speed to faster than 800 ms/sphere with a 100% success rate (<i>N</i> = 100). To extend this manipulation technique, 2D and 3D assembly that manipulates several objects is attained by compensating the positional error. Finally, we succeed in assembling 80–120 µm of microbeads and spheroids integrated by NIH3T3 cells. |
| first_indexed | 2024-03-10T19:37:42Z |
| format | Article |
| id | doaj.art-6807255ad1204fdf81dbff028f86e576 |
| institution | Directory Open Access Journal |
| issn | 2072-666X |
| language | English |
| last_indexed | 2024-03-10T19:37:42Z |
| publishDate | 2020-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Micromachines |
| spelling | doaj.art-6807255ad1204fdf81dbff028f86e5762023-11-20T01:33:12ZengMDPI AGMicromachines2072-666X2020-05-0111553410.3390/mi11050534High-Speed Manipulation of Microobjects Using an Automated Two-Fingered Microhand for 3D MicroassemblyEunhye Kim0Masaru Kojima1Yasushi Mae2Tatsuo Arai3Department of Systems Innovation, Graduate School of Engineering Science, Osaka University, Osaka 560-8531, JapanDepartment of Systems Innovation, Graduate School of Engineering Science, Osaka University, Osaka 560-8531, JapanFaculty of Engineering Science, Kansai University, Osaka 564-8680, JapanGlobal Alliance Laboratory, The University of Electro-Communications, Tokyo 182-8585, JapanTo assemble microobjects including biological cells quickly and precisely, a fully automated pick-and-place operation is applied. In micromanipulation in liquid, the challenges include strong adhesion forces and high dynamic viscosity. To solve these problems, a reliable manipulation system and special releasing techniques are indispensable. A microhand having dexterous motion is utilized to grasp an object stably, and an automated stage transports the object quickly. To detach the object adhered to one of the end effectors, two releasing methods—local stream and a dynamic releasing—are utilized. A system using vision-based techniques for the recognition of two fingertips and an object, as well automated releasing methods, can increase the manipulation speed to faster than 800 ms/sphere with a 100% success rate (<i>N</i> = 100). To extend this manipulation technique, 2D and 3D assembly that manipulates several objects is attained by compensating the positional error. Finally, we succeed in assembling 80–120 µm of microbeads and spheroids integrated by NIH3T3 cells.https://www.mdpi.com/2072-666X/11/5/5343D assemblyautomatic releasinglocal streamhigh-speed motionmicromanipulationtissue engineering |
| spellingShingle | Eunhye Kim Masaru Kojima Yasushi Mae Tatsuo Arai High-Speed Manipulation of Microobjects Using an Automated Two-Fingered Microhand for 3D Microassembly Micromachines 3D assembly automatic releasing local stream high-speed motion micromanipulation tissue engineering |
| title | High-Speed Manipulation of Microobjects Using an Automated Two-Fingered Microhand for 3D Microassembly |
| title_full | High-Speed Manipulation of Microobjects Using an Automated Two-Fingered Microhand for 3D Microassembly |
| title_fullStr | High-Speed Manipulation of Microobjects Using an Automated Two-Fingered Microhand for 3D Microassembly |
| title_full_unstemmed | High-Speed Manipulation of Microobjects Using an Automated Two-Fingered Microhand for 3D Microassembly |
| title_short | High-Speed Manipulation of Microobjects Using an Automated Two-Fingered Microhand for 3D Microassembly |
| title_sort | high speed manipulation of microobjects using an automated two fingered microhand for 3d microassembly |
| topic | 3D assembly automatic releasing local stream high-speed motion micromanipulation tissue engineering |
| url | https://www.mdpi.com/2072-666X/11/5/534 |
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