Successful management of diffuse unilateral subacute neuroretinitis with anthelmintics, and intravitreal triamcinolone followed by laser photocoagulation

Purpose: Diffuse unilateral subacute neuroretinitis (DUSN), a form of posterior uveitis, is secondary to the presence of a highly motile nematode in the intraretinal or subretinal space. Herein, we report a case of DUSN that was successfully managed by an intravitreal injection of triamcinolone and...

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Main Authors: Behzad Safarpour Lima, Alireza Ramezani, Masoud Soheilian, Ali Rastegarpour, Danial Roshandel, Shima Sayanjali
Format: Article
Language:English
Published: Knowledge E 2016-01-01
Series:Journal of Ophthalmic & Vision Research
Subjects:
Online Access:http://www.jovr.org/article.asp?issn=2008-322X;year=2016;volume=11;issue=1;spage=116;epage=119;aulast=Lima
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author Behzad Safarpour Lima
Alireza Ramezani
Masoud Soheilian
Ali Rastegarpour
Danial Roshandel
Shima Sayanjali
author_facet Behzad Safarpour Lima
Alireza Ramezani
Masoud Soheilian
Ali Rastegarpour
Danial Roshandel
Shima Sayanjali
author_sort Behzad Safarpour Lima
collection DOAJ
description Purpose: Diffuse unilateral subacute neuroretinitis (DUSN), a form of posterior uveitis, is secondary to the presence of a highly motile nematode in the intraretinal or subretinal space. Herein, we report a case of DUSN that was successfully managed by an intravitreal injection of triamcinolone and laser therapy. Case Report: A middle-aged man with complaint of decreased vision and marked unilateral vitritis and neuroretinitis. Fluorescein angiography revealed disc leakage, vessel wall staining, and diffuse track-like transmission defects of the RPE. Optical coherence tomography confirmed the subretinal location of the worm. The patient received oral thiabendazole and an intravitreal injection of triamcinolone acetonide. After 10 days, media haziness decreased, and a live motile subretinal worm was identified. Direct laser photocoagulation was performed to destroy the worm. After two months, a localized chorioretinal scar developed and no further active inflammation and subretinal worms were detected. Conclusion: Intravitreal steroids can be used safely in cases with DUSN and may help detect the causative worm for applying laser photocoagulation.
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spelling doaj.art-6809d2b33b6e41e6bb48a7a5d032d2d02022-12-22T03:55:46ZengKnowledge EJournal of Ophthalmic & Vision Research2008-322X2016-01-0111111611910.4103/2008-322X.180704Successful management of diffuse unilateral subacute neuroretinitis with anthelmintics, and intravitreal triamcinolone followed by laser photocoagulationBehzad Safarpour LimaAlireza RamezaniMasoud SoheilianAli RastegarpourDanial RoshandelShima SayanjaliPurpose: Diffuse unilateral subacute neuroretinitis (DUSN), a form of posterior uveitis, is secondary to the presence of a highly motile nematode in the intraretinal or subretinal space. Herein, we report a case of DUSN that was successfully managed by an intravitreal injection of triamcinolone and laser therapy. Case Report: A middle-aged man with complaint of decreased vision and marked unilateral vitritis and neuroretinitis. Fluorescein angiography revealed disc leakage, vessel wall staining, and diffuse track-like transmission defects of the RPE. Optical coherence tomography confirmed the subretinal location of the worm. The patient received oral thiabendazole and an intravitreal injection of triamcinolone acetonide. After 10 days, media haziness decreased, and a live motile subretinal worm was identified. Direct laser photocoagulation was performed to destroy the worm. After two months, a localized chorioretinal scar developed and no further active inflammation and subretinal worms were detected. Conclusion: Intravitreal steroids can be used safely in cases with DUSN and may help detect the causative worm for applying laser photocoagulation.http://www.jovr.org/article.asp?issn=2008-322X;year=2016;volume=11;issue=1;spage=116;epage=119;aulast=LimaDiffuse Unilateral Subacute Neuroretinitis; Intravitreal Triamcinolone; Laser Photocoagulation; Thiabendazole
spellingShingle Behzad Safarpour Lima
Alireza Ramezani
Masoud Soheilian
Ali Rastegarpour
Danial Roshandel
Shima Sayanjali
Successful management of diffuse unilateral subacute neuroretinitis with anthelmintics, and intravitreal triamcinolone followed by laser photocoagulation
Journal of Ophthalmic & Vision Research
Diffuse Unilateral Subacute Neuroretinitis; Intravitreal Triamcinolone; Laser Photocoagulation; Thiabendazole
title Successful management of diffuse unilateral subacute neuroretinitis with anthelmintics, and intravitreal triamcinolone followed by laser photocoagulation
title_full Successful management of diffuse unilateral subacute neuroretinitis with anthelmintics, and intravitreal triamcinolone followed by laser photocoagulation
title_fullStr Successful management of diffuse unilateral subacute neuroretinitis with anthelmintics, and intravitreal triamcinolone followed by laser photocoagulation
title_full_unstemmed Successful management of diffuse unilateral subacute neuroretinitis with anthelmintics, and intravitreal triamcinolone followed by laser photocoagulation
title_short Successful management of diffuse unilateral subacute neuroretinitis with anthelmintics, and intravitreal triamcinolone followed by laser photocoagulation
title_sort successful management of diffuse unilateral subacute neuroretinitis with anthelmintics and intravitreal triamcinolone followed by laser photocoagulation
topic Diffuse Unilateral Subacute Neuroretinitis; Intravitreal Triamcinolone; Laser Photocoagulation; Thiabendazole
url http://www.jovr.org/article.asp?issn=2008-322X;year=2016;volume=11;issue=1;spage=116;epage=119;aulast=Lima
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