Epidermolysis bullosa acquisita following skin graft in donor and graft sites: A case report

Epidermolysis bullosa acquisita is a rare mucocutaneous autoimmune blistering disorder which usually presents in adulthood. The disease is mediated by antibodies against type VII collagen, though the precise inciting factors for autoantibody formation are unknown. Here, we present the case of a 69-y...

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Bibliographic Details
Main Authors: Joyce Xia, Alice J. Tan, Gunnlaugur P. Nielsen, Ruth K. Foreman, Mai Hoang, Sean A. Hickey, Daniela Kroshinsky
Format: Article
Language:English
Published: Elsevier 2023-10-01
Series:Burns Open
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Online Access:http://www.sciencedirect.com/science/article/pii/S2468912223000196
Description
Summary:Epidermolysis bullosa acquisita is a rare mucocutaneous autoimmune blistering disorder which usually presents in adulthood. The disease is mediated by antibodies against type VII collagen, though the precise inciting factors for autoantibody formation are unknown. Here, we present the case of a 69-year-old man who developed this condition following autograft. We highlight this case to draw attention to a rare cause of skin graft failure, with early referral to specialist care necessary for avoidance of sequelae related to scarring.
ISSN:2468-9122