Analysis of Prevalence and Clinical Features of Ameloblastoma and its Histopathological Subtypes in Southeast Myanmar and Lower Northern Thailand Populations: A 13-Year Retrospective Study
Introduction: Prevalence of ameloblastomas has been established worldwide but collective data of ameloblastoma in Southeast Asian countries has not been well analyzed. Aim: Aim of this study was to report analysis and comparison of the prevalence and demographic data of clinical features of ame...
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| Format: | Article |
| Language: | English |
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JCDR Research and Publications Private Limited
2017-01-01
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| Series: | Journal of Clinical and Diagnostic Research |
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| Online Access: | https://jcdr.net/articles/PDF/9295/23629_CE[Ra]_F(DK)_PF1(DK_NE)_PFA(DK)_PF2(SH_DK).pdf |
| _version_ | 1818778648310710272 |
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| author | Chaidan Intapa |
| author_facet | Chaidan Intapa |
| author_sort | Chaidan Intapa |
| collection | DOAJ |
| description | Introduction: Prevalence of ameloblastomas has been
established worldwide but collective data of ameloblastoma in
Southeast Asian countries has not been well analyzed.
Aim: Aim of this study was to report analysis and comparison
of the prevalence and demographic data of clinical features of
ameloblastoma and its histopathological variants in Southeast
Myanmar and lower Northern Thailand populations.
Materials and Methods: A retrospective study on ameloblastoma
was performed based on the availability of oral biopsy specimens
in Faculty of Dentistry, Naresuan University, Phitsanulok, Thailand,
between January 2002 and August 2015. The collected data
were subjected to descriptive statistical analyses with the SPSS
version 17.0 statistical software package (SPSS Inc., Chicago,
USA). Pearson’s chi square (χ2
) test and t-test were employed.
The critical level of significance was set at p<0.05.
Results: Total of 616 cases were reviewed, 30 cases (5%)
were diagnosed as ameloblastoma with male:female ratio of
1.14:1. The mean age of the patients was 31.3±15.6 years.
The predominance anatomical distribution was observed in
the mandible (86.7%). Posterior body-ramus-angle region was
the most common site. Almost all cases were asyptomatic
and most common clinical manifestation was swelling of
affected region. Multilocular radiolucency was observed in
70% of cases, whereas 30% were unilocular. Three subtypes
of ameloblastomas were diagnosed: unicystic ameloblastoma
(20%), conventional solid/multicystic ameloblastoma (70%),
and desmoplastic ameloblastoma (10%). The most common
histologic pattern was the plexiform type (57.2%) followed by
follicular type (23.8%).
Conclusion: Prevalence of ameloblastoma in Southeast
Myanmar and lower Northern Thailand populations correspond
with data from other geographic areas of Thailand and other Asian
countries. However, some demographic and histopathological
profiles are different, with plexiform ameloblastoma being the
most common subtype in this study. |
| first_indexed | 2024-12-18T11:48:04Z |
| format | Article |
| id | doaj.art-680c12ca57f2493886ceae0a3345eb5d |
| institution | Directory Open Access Journal |
| issn | 2249-782X 0973-709X |
| language | English |
| last_indexed | 2024-12-18T11:48:04Z |
| publishDate | 2017-01-01 |
| publisher | JCDR Research and Publications Private Limited |
| record_format | Article |
| series | Journal of Clinical and Diagnostic Research |
| spelling | doaj.art-680c12ca57f2493886ceae0a3345eb5d2022-12-21T21:09:13ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2017-01-01111ZC102ZC10610.7860/JCDR/2017/23629.9295Analysis of Prevalence and Clinical Features of Ameloblastoma and its Histopathological Subtypes in Southeast Myanmar and Lower Northern Thailand Populations: A 13-Year Retrospective StudyChaidan Intapa0Department of Oral Diagnosis, Faculty of Dentistry, Naresuan University, Muang, Phitasanulok, Thailand.Introduction: Prevalence of ameloblastomas has been established worldwide but collective data of ameloblastoma in Southeast Asian countries has not been well analyzed. Aim: Aim of this study was to report analysis and comparison of the prevalence and demographic data of clinical features of ameloblastoma and its histopathological variants in Southeast Myanmar and lower Northern Thailand populations. Materials and Methods: A retrospective study on ameloblastoma was performed based on the availability of oral biopsy specimens in Faculty of Dentistry, Naresuan University, Phitsanulok, Thailand, between January 2002 and August 2015. The collected data were subjected to descriptive statistical analyses with the SPSS version 17.0 statistical software package (SPSS Inc., Chicago, USA). Pearson’s chi square (χ2 ) test and t-test were employed. The critical level of significance was set at p<0.05. Results: Total of 616 cases were reviewed, 30 cases (5%) were diagnosed as ameloblastoma with male:female ratio of 1.14:1. The mean age of the patients was 31.3±15.6 years. The predominance anatomical distribution was observed in the mandible (86.7%). Posterior body-ramus-angle region was the most common site. Almost all cases were asyptomatic and most common clinical manifestation was swelling of affected region. Multilocular radiolucency was observed in 70% of cases, whereas 30% were unilocular. Three subtypes of ameloblastomas were diagnosed: unicystic ameloblastoma (20%), conventional solid/multicystic ameloblastoma (70%), and desmoplastic ameloblastoma (10%). The most common histologic pattern was the plexiform type (57.2%) followed by follicular type (23.8%). Conclusion: Prevalence of ameloblastoma in Southeast Myanmar and lower Northern Thailand populations correspond with data from other geographic areas of Thailand and other Asian countries. However, some demographic and histopathological profiles are different, with plexiform ameloblastoma being the most common subtype in this study.https://jcdr.net/articles/PDF/9295/23629_CE[Ra]_F(DK)_PF1(DK_NE)_PFA(DK)_PF2(SH_DK).pdfmandiblemenmultilocularplexiformsoutheast asia |
| spellingShingle | Chaidan Intapa Analysis of Prevalence and Clinical Features of Ameloblastoma and its Histopathological Subtypes in Southeast Myanmar and Lower Northern Thailand Populations: A 13-Year Retrospective Study Journal of Clinical and Diagnostic Research mandible men multilocular plexiform southeast asia |
| title | Analysis of Prevalence and Clinical Features of Ameloblastoma and its Histopathological Subtypes in Southeast Myanmar and Lower Northern Thailand Populations: A 13-Year Retrospective Study |
| title_full | Analysis of Prevalence and Clinical Features of Ameloblastoma and its Histopathological Subtypes in Southeast Myanmar and Lower Northern Thailand Populations: A 13-Year Retrospective Study |
| title_fullStr | Analysis of Prevalence and Clinical Features of Ameloblastoma and its Histopathological Subtypes in Southeast Myanmar and Lower Northern Thailand Populations: A 13-Year Retrospective Study |
| title_full_unstemmed | Analysis of Prevalence and Clinical Features of Ameloblastoma and its Histopathological Subtypes in Southeast Myanmar and Lower Northern Thailand Populations: A 13-Year Retrospective Study |
| title_short | Analysis of Prevalence and Clinical Features of Ameloblastoma and its Histopathological Subtypes in Southeast Myanmar and Lower Northern Thailand Populations: A 13-Year Retrospective Study |
| title_sort | analysis of prevalence and clinical features of ameloblastoma and its histopathological subtypes in southeast myanmar and lower northern thailand populations a 13 year retrospective study |
| topic | mandible men multilocular plexiform southeast asia |
| url | https://jcdr.net/articles/PDF/9295/23629_CE[Ra]_F(DK)_PF1(DK_NE)_PFA(DK)_PF2(SH_DK).pdf |
| work_keys_str_mv | AT chaidanintapa analysisofprevalenceandclinicalfeaturesofameloblastomaanditshistopathologicalsubtypesinsoutheastmyanmarandlowernorthernthailandpopulationsa13yearretrospectivestudy |