Effect of vitamin-D supplementation on self-perceived health-related quality of life in postmenopausal women in Ludhiana, Punjab

Postmenopausal women are routinely prescribed calcium and Vitamin-D supplements in view of their increased risk of osteoporosis and fractures. A community-based interventional study was undertaken to determine the effect of Vitamin-D supplementation on self-perceived health-related quality of life i...

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Main Authors: Nimila Elsa Mathews, Paramita Sengupta, Anoop Ivan Benjamin
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2021-01-01
Series:Indian Journal of Public Health
Subjects:
Online Access:http://www.ijph.in/article.asp?issn=0019-557X;year=2021;volume=65;issue=3;spage=294;epage=297;aulast=Mathews
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author Nimila Elsa Mathews
Paramita Sengupta
Anoop Ivan Benjamin
author_facet Nimila Elsa Mathews
Paramita Sengupta
Anoop Ivan Benjamin
author_sort Nimila Elsa Mathews
collection DOAJ
description Postmenopausal women are routinely prescribed calcium and Vitamin-D supplements in view of their increased risk of osteoporosis and fractures. A community-based interventional study was undertaken to determine the effect of Vitamin-D supplementation on self-perceived health-related quality of life in 290 postmenopausal women over 6 months in 2015. Vitamin D (60,000 IU) was supplemented for 8 weeks. The CDC-Health-Related Quality-of-Life Questionnaire -14 was administered to the subjects at baseline and post intervention. The pre and postintervention responses were compared using Chi-square test and paired t-test as appropriate. There was a significant improvement in their overall general health status. Mean systolic blood pressure (BP) was reduced by 3.0% (P = 0.0705) and the mean diastolic BP by 3.2% (P = 0.0419). Post supplementation, high serum Vitamin-D levels was observed in 6.5% of the 92 subjects tested. Prescribing Vitamin D to postmenopausal women without checking the serum levels prior to supplementation may occasionally lead to toxicity.
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spelling doaj.art-68101de1eccd419bbe0b906a1be2fe8e2022-12-21T20:40:22ZengWolters Kluwer Medknow PublicationsIndian Journal of Public Health0019-557X2021-01-0165329429710.4103/ijph.IJPH_226_21Effect of vitamin-D supplementation on self-perceived health-related quality of life in postmenopausal women in Ludhiana, PunjabNimila Elsa MathewsParamita SenguptaAnoop Ivan BenjaminPostmenopausal women are routinely prescribed calcium and Vitamin-D supplements in view of their increased risk of osteoporosis and fractures. A community-based interventional study was undertaken to determine the effect of Vitamin-D supplementation on self-perceived health-related quality of life in 290 postmenopausal women over 6 months in 2015. Vitamin D (60,000 IU) was supplemented for 8 weeks. The CDC-Health-Related Quality-of-Life Questionnaire -14 was administered to the subjects at baseline and post intervention. The pre and postintervention responses were compared using Chi-square test and paired t-test as appropriate. There was a significant improvement in their overall general health status. Mean systolic blood pressure (BP) was reduced by 3.0% (P = 0.0705) and the mean diastolic BP by 3.2% (P = 0.0419). Post supplementation, high serum Vitamin-D levels was observed in 6.5% of the 92 subjects tested. Prescribing Vitamin D to postmenopausal women without checking the serum levels prior to supplementation may occasionally lead to toxicity.http://www.ijph.in/article.asp?issn=0019-557X;year=2021;volume=65;issue=3;spage=294;epage=297;aulast=Mathewshealth-related quality of lifepostmenopausal womenvitamin-d supplementation
spellingShingle Nimila Elsa Mathews
Paramita Sengupta
Anoop Ivan Benjamin
Effect of vitamin-D supplementation on self-perceived health-related quality of life in postmenopausal women in Ludhiana, Punjab
Indian Journal of Public Health
health-related quality of life
postmenopausal women
vitamin-d supplementation
title Effect of vitamin-D supplementation on self-perceived health-related quality of life in postmenopausal women in Ludhiana, Punjab
title_full Effect of vitamin-D supplementation on self-perceived health-related quality of life in postmenopausal women in Ludhiana, Punjab
title_fullStr Effect of vitamin-D supplementation on self-perceived health-related quality of life in postmenopausal women in Ludhiana, Punjab
title_full_unstemmed Effect of vitamin-D supplementation on self-perceived health-related quality of life in postmenopausal women in Ludhiana, Punjab
title_short Effect of vitamin-D supplementation on self-perceived health-related quality of life in postmenopausal women in Ludhiana, Punjab
title_sort effect of vitamin d supplementation on self perceived health related quality of life in postmenopausal women in ludhiana punjab
topic health-related quality of life
postmenopausal women
vitamin-d supplementation
url http://www.ijph.in/article.asp?issn=0019-557X;year=2021;volume=65;issue=3;spage=294;epage=297;aulast=Mathews
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AT paramitasengupta effectofvitamindsupplementationonselfperceivedhealthrelatedqualityoflifeinpostmenopausalwomeninludhianapunjab
AT anoopivanbenjamin effectofvitamindsupplementationonselfperceivedhealthrelatedqualityoflifeinpostmenopausalwomeninludhianapunjab