CUR5g, a novel autophagy inhibitor, exhibits potent synergistic anticancer effects with cisplatin against non-small-cell lung cancer

CUR5g, a novel autophagy inhibitor, exhibits potent synergistic anticancer effects with cisplatin against non-small-cell lung cancer

Abstract Autophagy, a highly conserved degradation process of eukaryotic cells, has been proven to be closely related to chemoresistance and metastasis of non-small-cell lung cancer (NSCLC). Autophagy inhibitors, such as chloroquine (CQ) and its derivative hydroxychloroquine (HCQ), has been shown to...

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Bibliographic Details
Main Authors: Jingxuan Chen, Yunpeng Shen, Bowen Wu, Peichang Yang, Gangchun Sun, Xiaoting Liu, Pengfei Qiang, Yamei Gao, Fangfang Sha, Zirui Li, Lu Zhang
Format: Article
Language:English
Published: Nature Publishing Group 2022-10-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-022-01217-9

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