Insulin glargine: pharmacokinetic and pharmacodynamic basis of clinical effect
Glargine became the first long-acting insulin analogue. Glargine was designed to meet basal insulin requirements throughout the day with a single injection. Pharmacokinetics of insulin glargine is characterized by biotransformation into metabolites M1 and M2 that transforms the B chain of glargine s...
Autori principali: | , |
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Natura: | Articolo |
Lingua: | English |
Pubblicazione: |
Endocrinology Research Centre
2014-12-01
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Serie: | Сахарный диабет |
Soggetti: | |
Accesso online: | https://www.dia-endojournals.ru/jour/article/view/6691 |