Modelling Renal Filtration and Reabsorption Processes in a Human Glomerulus and Proximal Tubule Microphysiological System

Modelling Renal Filtration and Reabsorption Processes in a Human Glomerulus and Proximal Tubule Microphysiological System

Kidney microphysiological systems (MPS) serve as potentially valuable preclinical instruments in probing mechanisms of renal clearance and osmoregulation. Current kidney MPS models target regions of the nephron, such as the glomerulus and proximal tubule (PCT), but fail to incorporate multiple filtr...

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Bibliographic Details
Main Authors: Stephanie Y. Zhang, Gretchen J. Mahler
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Micromachines
Subjects:
kidney
cytoskeleton
microfluidics
cytotoxicity
pharmacokinetics
Online Access:https://www.mdpi.com/2072-666X/12/8/983

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