Regulatory γδ T cells induced by G-CSF participate in acute graft-versus-host disease regulation in G-CSF-mobilized allogeneic peripheral blood stem cell transplantation

Regulatory γδ T cells induced by G-CSF participate in acute graft-versus-host disease regulation in G-CSF-mobilized allogeneic peripheral blood stem cell transplantation

Abstract Background The immunomodulatory effects of granulocyte colony-stimulating factor (G-CSF) on T cells result in a low incidence of acute graft-versus-host disease (aGVHD) in G-CSF-mobilized allogeneic peripheral blood stem cell transplantation (G-PBSCT). However, the exact mechanism remains u...

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Bibliographic Details
Main Authors: Li Xuan, Xiuli Wu, Dan Qiu, Li Gao, Hui Liu, Zhiping Fan, Fen Huang, Zhenyi Jin, Jing Sun, Yangqiu Li, Qifa Liu
Format: Article
Language:English
Published: BMC 2018-05-01
Series:Journal of Translational Medicine
Subjects:
Acute graft-versus-host disease
Allogeneic peripheral blood stem cell transplantation
Granulocyte colony-stimulating factor
Regulatory γδ T cells
Online Access:http://link.springer.com/article/10.1186/s12967-018-1519-2

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