Generation and characterization of FMR1 knockout zebrafish.
Fragile X syndrome (FXS) is one of the most common known causes of inherited mental retardation. The gene mutated in FXS is named FMR1, and is well conserved from human to Drosophila. In order to generate a genetic tool to study FMR1 function during vertebrate development, we generated two mutant al...
Main Authors: | Marjo J den Broeder, Herma van der Linde, Judith R Brouwer, Ben A Oostra, Rob Willemsen, René F Ketting |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2009-11-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC2774943?pdf=render |
Similar Items
-
Altered cortical Cytoarchitecture in the Fmr1 knockout mouse
by: Frankie H. F. Lee, et al.
Published: (2019-06-01) -
Generation and characterization of a novel gne Knockout Model in Zebrafish
by: Hagay Livne, et al.
Published: (2022-10-01) -
The generation of a conditional Fmr1 knock out mouse model to study Fmrp function in vivo
by: E.J. Mientjes, et al.
Published: (2006-03-01) -
BDNF and TrkB in neuronal differentiation of Fmr1-knockout mouse
by: Verna Louhivuori, et al.
Published: (2011-02-01) -
Dietary rescue of adult behavioral deficits in the Fmr1 knockout mouse.
by: Suzanne O Nolan, et al.
Published: (2022-01-01)