Endoscopic endonasal resection of two rare cases of hemangiopericytomas invading the cavernous sinus and literature review
Hemangiopericytomas (HPCs) invading the cavernous sinus (CS) are extremely rare invasive tumors that have a great propensity for local recurrence. To date, only eight cases have been reported in the literature. Owing to the abundant vascular supply of HPCs, intracavernous bleeding and important bloo...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2022-10-01
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| Series: | Frontiers in Surgery |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fsurg.2022.1035635/full |
| _version_ | 1811197413712461824 |
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| author | Yingxi Wu Li Gong Yunze Zhang Min Zheng Junting Li Junting Li Yafei Xue Yan Qu Tianzhi Zhao |
| author_facet | Yingxi Wu Li Gong Yunze Zhang Min Zheng Junting Li Junting Li Yafei Xue Yan Qu Tianzhi Zhao |
| author_sort | Yingxi Wu |
| collection | DOAJ |
| description | Hemangiopericytomas (HPCs) invading the cavernous sinus (CS) are extremely rare invasive tumors that have a great propensity for local recurrence. To date, only eight cases have been reported in the literature. Owing to the abundant vascular supply of HPCs, intracavernous bleeding and important blood vessels and nerves passing through the CS, it is very difficult and challenging for neurosurgeons to completely resect HPCs. Here, we report two cases of HPCs invading the CS and introduce their clinical manifestations, imaging findings, surgical approaches and histopathological features in detail. We have implemented the surgery by the endoscopic transpterygoid transcavernous approach (ETPTCa) for the two patients, and one patient has undergone gross total resection (GTR) and another has undergone subtotal resection (STR) and postoperative stereotactic radiosurgery (SRS). The ETPTCa may serve as a viable option to facilitate HPCs resection. Radiotherapy is helpful in prolonging progression-free survival (PFS) following STR of the tumor. |
| first_indexed | 2024-04-12T01:14:25Z |
| format | Article |
| id | doaj.art-681885aacde94735aafb0923fdf4432d |
| institution | Directory Open Access Journal |
| issn | 2296-875X |
| language | English |
| last_indexed | 2024-04-12T01:14:25Z |
| publishDate | 2022-10-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Surgery |
| spelling | doaj.art-681885aacde94735aafb0923fdf4432d2022-12-22T03:54:01ZengFrontiers Media S.A.Frontiers in Surgery2296-875X2022-10-01910.3389/fsurg.2022.10356351035635Endoscopic endonasal resection of two rare cases of hemangiopericytomas invading the cavernous sinus and literature reviewYingxi Wu0Li Gong1Yunze Zhang2Min Zheng3Junting Li4Junting Li5Yafei Xue6Yan Qu7Tianzhi Zhao8Department of Neurosurgery, Tangdu Hospital, Air Force Medical University, Xi’an, ChinaDepartment of Pathology, Tangdu Hospital, Air Force Medical University, Xi’an, ChinaDepartment of Neurosurgery, Tangdu Hospital, Air Force Medical University, Xi’an, ChinaDepartment of Neurosurgery, Tangdu Hospital, Air Force Medical University, Xi’an, ChinaDepartment of Neurosurgery, Tangdu Hospital, Air Force Medical University, Xi’an, ChinaDepartment of Pathology, Tangdu Hospital, Air Force Medical University, Xi’an, ChinaDepartment of Neurosurgery, Tangdu Hospital, Air Force Medical University, Xi’an, ChinaDepartment of Neurosurgery, Tangdu Hospital, Air Force Medical University, Xi’an, ChinaDepartment of Neurosurgery, Tangdu Hospital, Air Force Medical University, Xi’an, ChinaHemangiopericytomas (HPCs) invading the cavernous sinus (CS) are extremely rare invasive tumors that have a great propensity for local recurrence. To date, only eight cases have been reported in the literature. Owing to the abundant vascular supply of HPCs, intracavernous bleeding and important blood vessels and nerves passing through the CS, it is very difficult and challenging for neurosurgeons to completely resect HPCs. Here, we report two cases of HPCs invading the CS and introduce their clinical manifestations, imaging findings, surgical approaches and histopathological features in detail. We have implemented the surgery by the endoscopic transpterygoid transcavernous approach (ETPTCa) for the two patients, and one patient has undergone gross total resection (GTR) and another has undergone subtotal resection (STR) and postoperative stereotactic radiosurgery (SRS). The ETPTCa may serve as a viable option to facilitate HPCs resection. Radiotherapy is helpful in prolonging progression-free survival (PFS) following STR of the tumor.https://www.frontiersin.org/articles/10.3389/fsurg.2022.1035635/fullhemangiopericytomascavernous sinusendoscopic endonasal approachneuroimaginghistopathologyradiotherapy |
| spellingShingle | Yingxi Wu Li Gong Yunze Zhang Min Zheng Junting Li Junting Li Yafei Xue Yan Qu Tianzhi Zhao Endoscopic endonasal resection of two rare cases of hemangiopericytomas invading the cavernous sinus and literature review Frontiers in Surgery hemangiopericytomas cavernous sinus endoscopic endonasal approach neuroimaging histopathology radiotherapy |
| title | Endoscopic endonasal resection of two rare cases of hemangiopericytomas invading the cavernous sinus and literature review |
| title_full | Endoscopic endonasal resection of two rare cases of hemangiopericytomas invading the cavernous sinus and literature review |
| title_fullStr | Endoscopic endonasal resection of two rare cases of hemangiopericytomas invading the cavernous sinus and literature review |
| title_full_unstemmed | Endoscopic endonasal resection of two rare cases of hemangiopericytomas invading the cavernous sinus and literature review |
| title_short | Endoscopic endonasal resection of two rare cases of hemangiopericytomas invading the cavernous sinus and literature review |
| title_sort | endoscopic endonasal resection of two rare cases of hemangiopericytomas invading the cavernous sinus and literature review |
| topic | hemangiopericytomas cavernous sinus endoscopic endonasal approach neuroimaging histopathology radiotherapy |
| url | https://www.frontiersin.org/articles/10.3389/fsurg.2022.1035635/full |
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