RNA N6-methyladenosine modulates endothelial atherogenic responses to disturbed flow in mice

RNA N6-methyladenosine modulates endothelial atherogenic responses to disturbed flow in mice

Atherosclerosis preferentially occurs in atheroprone vasculature where human umbilical vein endothelial cells are exposed to disturbed flow. Disturbed flow is associated with vascular inflammation and focal distribution. Recent studies have revealed the involvement of epigenetic regulation in athero...

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Bibliographic Details
Main Authors: Bochuan Li, Ting Zhang, Mengxia Liu, Zhen Cui, Yanhong Zhang, Mingming Liu, Yanan Liu, Yongqiao Sun, Mengqi Li, Yikui Tian, Ying Yang, Hongfeng Jiang, Degang Liang
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-01-01
Series:eLife
Subjects:
atherosclerosis
endothelial cell
Mettl3
EGFR
Online Access:https://elifesciences.org/articles/69906

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