Anti-Proliferative and Apoptosis-Inducing Effects of Camptothecin-20(s)-O-(2-pyrazolyl-1)acetic Ester in Human Breast Tumor MCF-7 Cells
Camptothecin-20(s)-O-(2-pyrazolyl-1)acetic ester (CPT6) is a novel semi-synthetic analog of camptothecin. In a previous report, CPT6 possessed higher cytotoxic activity in vitro towards human breast tumor MCF-7 cells than topotecan. In this study, the antitumor activity of CPT6 on the human breast...
Main Authors: | Chu Chu, Jialin Xu, Dongping Cheng, Xingnuo Li, Shengqiang Tong, Jizong Yan, Qingyong Li |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2014-04-01
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Series: | Molecules |
Subjects: | |
Online Access: | http://www.mdpi.com/1420-3049/19/4/4941 |
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