Macrophage Reprogramming with Anti‐miR223‐Loaded Artificial Protocells Enhances In Vivo Cancer Therapeutic Potential

Macrophage Reprogramming with Anti‐miR223‐Loaded Artificial Protocells Enhances In Vivo Cancer Therapeutic Potential

Abstract Several immune cell‐expressed miRNAs (miRs) are associated with altered prognostic outcome in cancer patients, suggesting that they may be potential targets for development of cancer therapies. Here, translucent zebrafish (Danio rerio) is utilized to demonstrate that genetic knockout or kno...

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Bibliographic Details
Main Authors: Paco López‐Cuevas, Can Xu, Charlotte E. Severn, Tiah C. L. Oates, Stephen J. Cross, Ashley M. Toye, Stephen Mann, Paul Martin
Format: Article
Language:English
Published: Wiley 2022-12-01
Series:Advanced Science
Subjects:
cancer
inflammation
macrophages
microRNA‐223
neutrophils
protocells
Online Access:https://doi.org/10.1002/advs.202202717

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