Refractive Lens Exchange Surgery in Early-Onset High Myopia Patients With Partial Cataract
PurposeBy reporting clinical characteristics and retinal image quality before and after refractive lens replacement surgery in early-onset high myopia (eoHM) patients presenting with partial cataract, we emphasized the need for an objective way to grade the severity of partial cataracts.MethodsThis...
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| Format: | Article |
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Frontiers Media S.A.
2022-04-01
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| Series: | Frontiers in Medicine |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fmed.2022.739197/full |
| _version_ | 1818264922180550656 |
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| author | Xi-Fang Zhang Xiao-Xia Li Chen Xin Brad Kline Meng-Tian Kang Meng Li Li-Ya Qiao Ning-Li Wang |
| author_facet | Xi-Fang Zhang Xiao-Xia Li Chen Xin Brad Kline Meng-Tian Kang Meng Li Li-Ya Qiao Ning-Li Wang |
| author_sort | Xi-Fang Zhang |
| collection | DOAJ |
| description | PurposeBy reporting clinical characteristics and retinal image quality before and after refractive lens replacement surgery in early-onset high myopia (eoHM) patients presenting with partial cataract, we emphasized the need for an objective way to grade the severity of partial cataracts.MethodsThis retrospective, consecutive case series included six Chinese patients (nine eyes). Analysis of previous medical records, visual acuity, optometry, retinal image quality, and axial length (AXL) before surgery and after surgery was performed.ResultsFive females and one male (nine eyes) with a mean (± SD) age of 11.6 ± 7.9 years (range: 4–25 years) were included in this study. The preoperative spherical power ranged from −7.5 to −42 D. The mean follow-up time was 36 months (range: 24–48 months). Phacoemulsification was followed by in-the-bag implantation of intraocular lens. For patients who were under 6 years old, posterior capsulotomy + anterior vitrectomy were performed simultaneously. All surgeries were uneventful and no postoperative complications occurred during the entire follow-up period. All patients’ uncorrected visual acuity improved by ≥2 lines postoperatively(Snellen acuity). LogMAR best-corrected visual acuity was improved at 24-month (P = 0.042) and endpoint (P = 0.046) follow-ups. Modulation transfer function cutoff frequency (MTFcutoff) and objective scatter index (OSI) was significantly improved at 12-month (P = 0.025, P = 0.038), 24-month (P = 0.005, P = 0.007) and endpoint (P = 0.005, P = 0.008) follow-ups. Postoperative AXL remained stable during 2–4 year follow-ups (P > 0.05).ConclusionRefractive lens replacement surgery is safe and effective for improving functional vision in eoHM patients presenting with partial cataract. Retinal image quality could provide a useful and objective way to facilitate partial cataract severity evaluation and surgery decision making. |
| first_indexed | 2024-12-12T19:42:36Z |
| format | Article |
| id | doaj.art-6821f2f3eb5d49d7a43bd877225f6b7b |
| institution | Directory Open Access Journal |
| issn | 2296-858X |
| language | English |
| last_indexed | 2024-12-12T19:42:36Z |
| publishDate | 2022-04-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Medicine |
| spelling | doaj.art-6821f2f3eb5d49d7a43bd877225f6b7b2022-12-22T00:14:10ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2022-04-01910.3389/fmed.2022.739197739197Refractive Lens Exchange Surgery in Early-Onset High Myopia Patients With Partial CataractXi-Fang Zhang0Xiao-Xia Li1Chen Xin2Brad Kline3Meng-Tian Kang4Meng Li5Li-Ya Qiao6Ning-Li Wang7Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology and Visual Sciences Key Laboratory, Beijing, ChinaBeijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology and Visual Sciences Key Laboratory, Beijing, ChinaBeijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology and Visual Sciences Key Laboratory, Beijing, ChinaDepartment of Ophthalmology, University of California, San Francisco, San Francisco, CA, United StatesBeijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology and Visual Sciences Key Laboratory, Beijing, ChinaBeijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology and Visual Sciences Key Laboratory, Beijing, ChinaBeijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology and Visual Sciences Key Laboratory, Beijing, ChinaBeijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology and Visual Sciences Key Laboratory, Beijing, ChinaPurposeBy reporting clinical characteristics and retinal image quality before and after refractive lens replacement surgery in early-onset high myopia (eoHM) patients presenting with partial cataract, we emphasized the need for an objective way to grade the severity of partial cataracts.MethodsThis retrospective, consecutive case series included six Chinese patients (nine eyes). Analysis of previous medical records, visual acuity, optometry, retinal image quality, and axial length (AXL) before surgery and after surgery was performed.ResultsFive females and one male (nine eyes) with a mean (± SD) age of 11.6 ± 7.9 years (range: 4–25 years) were included in this study. The preoperative spherical power ranged from −7.5 to −42 D. The mean follow-up time was 36 months (range: 24–48 months). Phacoemulsification was followed by in-the-bag implantation of intraocular lens. For patients who were under 6 years old, posterior capsulotomy + anterior vitrectomy were performed simultaneously. All surgeries were uneventful and no postoperative complications occurred during the entire follow-up period. All patients’ uncorrected visual acuity improved by ≥2 lines postoperatively(Snellen acuity). LogMAR best-corrected visual acuity was improved at 24-month (P = 0.042) and endpoint (P = 0.046) follow-ups. Modulation transfer function cutoff frequency (MTFcutoff) and objective scatter index (OSI) was significantly improved at 12-month (P = 0.025, P = 0.038), 24-month (P = 0.005, P = 0.007) and endpoint (P = 0.005, P = 0.008) follow-ups. Postoperative AXL remained stable during 2–4 year follow-ups (P > 0.05).ConclusionRefractive lens replacement surgery is safe and effective for improving functional vision in eoHM patients presenting with partial cataract. Retinal image quality could provide a useful and objective way to facilitate partial cataract severity evaluation and surgery decision making.https://www.frontiersin.org/articles/10.3389/fmed.2022.739197/fullearly-onset high myopiapartial cataractretinal image qualityrefractive lens replacement surgeryaxial length |
| spellingShingle | Xi-Fang Zhang Xiao-Xia Li Chen Xin Brad Kline Meng-Tian Kang Meng Li Li-Ya Qiao Ning-Li Wang Refractive Lens Exchange Surgery in Early-Onset High Myopia Patients With Partial Cataract Frontiers in Medicine early-onset high myopia partial cataract retinal image quality refractive lens replacement surgery axial length |
| title | Refractive Lens Exchange Surgery in Early-Onset High Myopia Patients With Partial Cataract |
| title_full | Refractive Lens Exchange Surgery in Early-Onset High Myopia Patients With Partial Cataract |
| title_fullStr | Refractive Lens Exchange Surgery in Early-Onset High Myopia Patients With Partial Cataract |
| title_full_unstemmed | Refractive Lens Exchange Surgery in Early-Onset High Myopia Patients With Partial Cataract |
| title_short | Refractive Lens Exchange Surgery in Early-Onset High Myopia Patients With Partial Cataract |
| title_sort | refractive lens exchange surgery in early onset high myopia patients with partial cataract |
| topic | early-onset high myopia partial cataract retinal image quality refractive lens replacement surgery axial length |
| url | https://www.frontiersin.org/articles/10.3389/fmed.2022.739197/full |
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