Scoping review of six retrospective studies: risk factors associated with the case fatality rate of people infected with Coronavirus (COVID-19)

Background: It would be rational to describe the pattern of the clinical characteristics of the survivors and the nonsurvivors during the critical intensive-infection era of coronavirus disease 2019 (COVID-19). The explicit objective of the current scoping review was to delineate the predictive risk...

Full description

Bibliographic Details
Main Authors: Adel Sadeq, Asim Ahmed Elnour, Farah Hamad Farah, Azza Ramadan, Judit Don, Ahmed Ibrahim Fathelrahman, Maisoun Alkaabi, Mohammed Baraka, Abubakar B Abubakar, Sasha Mohammed Elamin Suliman, Abdulla Al Amoodi, IsraaYousif Khidir, Khalid Awad Al Kubaisi, Nadia Al Mazroui
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2022-01-01
Series:Journal of Pharmacy and Bioallied Sciences
Subjects:
Online Access:http://www.jpbsonline.org/article.asp?issn=0975-7406;year=2022;volume=14;issue=2;spage=81;epage=92;aulast=Sadeq
_version_ 1798038379725586432
author Adel Sadeq
Asim Ahmed Elnour
Farah Hamad Farah
Azza Ramadan
Judit Don
Ahmed Ibrahim Fathelrahman
Maisoun Alkaabi
Mohammed Baraka
Abubakar B Abubakar
Sasha Mohammed Elamin Suliman
Abdulla Al Amoodi
IsraaYousif Khidir
Khalid Awad Al Kubaisi
Nadia Al Mazroui
author_facet Adel Sadeq
Asim Ahmed Elnour
Farah Hamad Farah
Azza Ramadan
Judit Don
Ahmed Ibrahim Fathelrahman
Maisoun Alkaabi
Mohammed Baraka
Abubakar B Abubakar
Sasha Mohammed Elamin Suliman
Abdulla Al Amoodi
IsraaYousif Khidir
Khalid Awad Al Kubaisi
Nadia Al Mazroui
author_sort Adel Sadeq
collection DOAJ
description Background: It would be rational to describe the pattern of the clinical characteristics of the survivors and the nonsurvivors during the critical intensive-infection era of coronavirus disease 2019 (COVID-19). The explicit objective of the current scoping review was to delineate the predictive risk factors associated with case fatality rate (CFR). Methods: Six retrospective studies of subjects infected with COVID-19 published between December 1, 2020, and March 30, 2020, describing nonsurvivors in Wuhan/Hubei, China, were identified. Results: There were 1769 subjects with a mean age of 52 years, and 65.9% were male. The highest comorbidity reported was cardiovascular diseases at 22.2% (393/1769). The overall number of cases admitted to the intensive care unit was 228 (12.9%). The reported overall CFR was 7.7% (136/1769), with the highest at 28.2% (54/191), and the lowest at 1.4% (15/1099). The mean duration of onset until death for nonsurvivors was 15.3 days. Conclusion: We have found that older age, male gender, the longer duration from onset till death (days), development of acute respiratory distress syndrome/shock, preexisting diabetes, and preexisting cardiovascular diseases were the major risk factors associated with high CFR.
first_indexed 2024-04-11T21:39:24Z
format Article
id doaj.art-6825f1c5cc9c49bc90557a6ec71dc3a0
institution Directory Open Access Journal
issn 0975-7406
language English
last_indexed 2024-04-11T21:39:24Z
publishDate 2022-01-01
publisher Wolters Kluwer Medknow Publications
record_format Article
series Journal of Pharmacy and Bioallied Sciences
spelling doaj.art-6825f1c5cc9c49bc90557a6ec71dc3a02022-12-22T04:01:38ZengWolters Kluwer Medknow PublicationsJournal of Pharmacy and Bioallied Sciences0975-74062022-01-01142819210.4103/jpbs.jpbs_460_21Scoping review of six retrospective studies: risk factors associated with the case fatality rate of people infected with Coronavirus (COVID-19)Adel SadeqAsim Ahmed ElnourFarah Hamad FarahAzza RamadanJudit DonAhmed Ibrahim FathelrahmanMaisoun AlkaabiMohammed BarakaAbubakar B AbubakarSasha Mohammed Elamin SulimanAbdulla Al AmoodiIsraaYousif KhidirKhalid Awad Al KubaisiNadia Al MazrouiBackground: It would be rational to describe the pattern of the clinical characteristics of the survivors and the nonsurvivors during the critical intensive-infection era of coronavirus disease 2019 (COVID-19). The explicit objective of the current scoping review was to delineate the predictive risk factors associated with case fatality rate (CFR). Methods: Six retrospective studies of subjects infected with COVID-19 published between December 1, 2020, and March 30, 2020, describing nonsurvivors in Wuhan/Hubei, China, were identified. Results: There were 1769 subjects with a mean age of 52 years, and 65.9% were male. The highest comorbidity reported was cardiovascular diseases at 22.2% (393/1769). The overall number of cases admitted to the intensive care unit was 228 (12.9%). The reported overall CFR was 7.7% (136/1769), with the highest at 28.2% (54/191), and the lowest at 1.4% (15/1099). The mean duration of onset until death for nonsurvivors was 15.3 days. Conclusion: We have found that older age, male gender, the longer duration from onset till death (days), development of acute respiratory distress syndrome/shock, preexisting diabetes, and preexisting cardiovascular diseases were the major risk factors associated with high CFR.http://www.jpbsonline.org/article.asp?issn=0975-7406;year=2022;volume=14;issue=2;spage=81;epage=92;aulast=Sadeqcase fatality ratecoronavirus disease 2019nonsurvivorspredictive risk factorssurvivors
spellingShingle Adel Sadeq
Asim Ahmed Elnour
Farah Hamad Farah
Azza Ramadan
Judit Don
Ahmed Ibrahim Fathelrahman
Maisoun Alkaabi
Mohammed Baraka
Abubakar B Abubakar
Sasha Mohammed Elamin Suliman
Abdulla Al Amoodi
IsraaYousif Khidir
Khalid Awad Al Kubaisi
Nadia Al Mazroui
Scoping review of six retrospective studies: risk factors associated with the case fatality rate of people infected with Coronavirus (COVID-19)
Journal of Pharmacy and Bioallied Sciences
case fatality rate
coronavirus disease 2019
nonsurvivors
predictive risk factors
survivors
title Scoping review of six retrospective studies: risk factors associated with the case fatality rate of people infected with Coronavirus (COVID-19)
title_full Scoping review of six retrospective studies: risk factors associated with the case fatality rate of people infected with Coronavirus (COVID-19)
title_fullStr Scoping review of six retrospective studies: risk factors associated with the case fatality rate of people infected with Coronavirus (COVID-19)
title_full_unstemmed Scoping review of six retrospective studies: risk factors associated with the case fatality rate of people infected with Coronavirus (COVID-19)
title_short Scoping review of six retrospective studies: risk factors associated with the case fatality rate of people infected with Coronavirus (COVID-19)
title_sort scoping review of six retrospective studies risk factors associated with the case fatality rate of people infected with coronavirus covid 19
topic case fatality rate
coronavirus disease 2019
nonsurvivors
predictive risk factors
survivors
url http://www.jpbsonline.org/article.asp?issn=0975-7406;year=2022;volume=14;issue=2;spage=81;epage=92;aulast=Sadeq
work_keys_str_mv AT adelsadeq scopingreviewofsixretrospectivestudiesriskfactorsassociatedwiththecasefatalityrateofpeopleinfectedwithcoronaviruscovid19
AT asimahmedelnour scopingreviewofsixretrospectivestudiesriskfactorsassociatedwiththecasefatalityrateofpeopleinfectedwithcoronaviruscovid19
AT farahhamadfarah scopingreviewofsixretrospectivestudiesriskfactorsassociatedwiththecasefatalityrateofpeopleinfectedwithcoronaviruscovid19
AT azzaramadan scopingreviewofsixretrospectivestudiesriskfactorsassociatedwiththecasefatalityrateofpeopleinfectedwithcoronaviruscovid19
AT juditdon scopingreviewofsixretrospectivestudiesriskfactorsassociatedwiththecasefatalityrateofpeopleinfectedwithcoronaviruscovid19
AT ahmedibrahimfathelrahman scopingreviewofsixretrospectivestudiesriskfactorsassociatedwiththecasefatalityrateofpeopleinfectedwithcoronaviruscovid19
AT maisounalkaabi scopingreviewofsixretrospectivestudiesriskfactorsassociatedwiththecasefatalityrateofpeopleinfectedwithcoronaviruscovid19
AT mohammedbaraka scopingreviewofsixretrospectivestudiesriskfactorsassociatedwiththecasefatalityrateofpeopleinfectedwithcoronaviruscovid19
AT abubakarbabubakar scopingreviewofsixretrospectivestudiesriskfactorsassociatedwiththecasefatalityrateofpeopleinfectedwithcoronaviruscovid19
AT sashamohammedelaminsuliman scopingreviewofsixretrospectivestudiesriskfactorsassociatedwiththecasefatalityrateofpeopleinfectedwithcoronaviruscovid19
AT abdullaalamoodi scopingreviewofsixretrospectivestudiesriskfactorsassociatedwiththecasefatalityrateofpeopleinfectedwithcoronaviruscovid19
AT israayousifkhidir scopingreviewofsixretrospectivestudiesriskfactorsassociatedwiththecasefatalityrateofpeopleinfectedwithcoronaviruscovid19
AT khalidawadalkubaisi scopingreviewofsixretrospectivestudiesriskfactorsassociatedwiththecasefatalityrateofpeopleinfectedwithcoronaviruscovid19
AT nadiaalmazroui scopingreviewofsixretrospectivestudiesriskfactorsassociatedwiththecasefatalityrateofpeopleinfectedwithcoronaviruscovid19