Analysis of Favipiravir Adverse Drug Reactions during COVID-19 Pandemic: A Retrospective Study Based on Iraqi Pharmacovigilance Center Database
The “severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)” was the reason behind the recent pandemic “COVID-19” that started from Wuhan, china, and rapidly spread to many regions of the world. Research in Drug repurposing processes to treat this novel coronavirus involved many medications,...
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| Format: | Article |
| Language: | English |
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College of Pharmacy / Mustansiriyah University
2024-04-01
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| Series: | Al-Mustansiriyah Journal of Pharmaceutical Sciences |
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| Online Access: | https://ajps.uomustansiriyah.edu.iq/index.php/AJPS/article/view/1069 |
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| author | Yasir Ezalden Noori Alkashab Inam S. Arif Manal M. Younus Mohammed M. Mohammed Abdullah M. Alrawi Salim Hamadi |
| author_facet | Yasir Ezalden Noori Alkashab Inam S. Arif Manal M. Younus Mohammed M. Mohammed Abdullah M. Alrawi Salim Hamadi |
| author_sort | Yasir Ezalden Noori Alkashab |
| collection | DOAJ |
| description |
The “severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)” was the reason behind the recent pandemic “COVID-19” that started from Wuhan, china, and rapidly spread to many regions of the world. Research in Drug repurposing processes to treat this novel coronavirus involved many medications,
one of the most discussed is Favipiravir. The objective of the current work was aimed towards Examining the cause, severity, preventability, predictability, and outcome of favipiravir-associated adverse events that had been reported in Iraq. In terms of adverse drug responses, "Gastrointestinal disorders" accounted for the majority (57.4%), followed by "Cardiac disorders" (35.2%), and "Investigations" (abnormal lab test results) (13%). The causality of these reactions Is majorly “Possible” (62%). Severity level 1 (40.9%) and 2 (41.8%). Ninety-nine percent of the ADRs are expected. The majority of the ADRs are non-Preventable (76.3%). The main outcome is Recovered / Resolved (44.5%). About (50%) of the ADRs were serious.
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| first_indexed | 2024-04-24T12:29:38Z |
| format | Article |
| id | doaj.art-682c0a25c23142ae881cae2566a285b2 |
| institution | Directory Open Access Journal |
| issn | 1815-0993 2959-183X |
| language | English |
| last_indexed | 2024-04-24T12:29:38Z |
| publishDate | 2024-04-01 |
| publisher | College of Pharmacy / Mustansiriyah University |
| record_format | Article |
| series | Al-Mustansiriyah Journal of Pharmaceutical Sciences |
| spelling | doaj.art-682c0a25c23142ae881cae2566a285b22024-04-08T06:58:16ZengCollege of Pharmacy / Mustansiriyah UniversityAl-Mustansiriyah Journal of Pharmaceutical Sciences1815-09932959-183X2024-04-0124210.32947/ajps.v24i2.1069Analysis of Favipiravir Adverse Drug Reactions during COVID-19 Pandemic: A Retrospective Study Based on Iraqi Pharmacovigilance Center DatabaseYasir Ezalden Noori Alkashab0Inam S. Arif1Manal M. Younus2Mohammed M. Mohammed3Abdullah M. Alrawi4Salim Hamadi5University of Mustansiriyah / College of PharmacyDepartment of Clinical Pharmacy, College of Pharmacy, Mustansiriyah University, Baghdad, IraqIraqi Pharmacovigilance Center, Ministry of Health, Baghdad, IraqDepartment of Clinical Pharmacy, College of Pharmacy, Mustansiriyah University, Baghdad, IraqBS Pharm, Mustansiriyah university department of pharmacology &Biomedical sciences, university of petra Amman Jordan The “severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)” was the reason behind the recent pandemic “COVID-19” that started from Wuhan, china, and rapidly spread to many regions of the world. Research in Drug repurposing processes to treat this novel coronavirus involved many medications, one of the most discussed is Favipiravir. The objective of the current work was aimed towards Examining the cause, severity, preventability, predictability, and outcome of favipiravir-associated adverse events that had been reported in Iraq. In terms of adverse drug responses, "Gastrointestinal disorders" accounted for the majority (57.4%), followed by "Cardiac disorders" (35.2%), and "Investigations" (abnormal lab test results) (13%). The causality of these reactions Is majorly “Possible” (62%). Severity level 1 (40.9%) and 2 (41.8%). Ninety-nine percent of the ADRs are expected. The majority of the ADRs are non-Preventable (76.3%). The main outcome is Recovered / Resolved (44.5%). About (50%) of the ADRs were serious. https://ajps.uomustansiriyah.edu.iq/index.php/AJPS/article/view/1069COVID-19 SARS-COV-2Favipiravircoronaviruspharmacovigilance Iraq |
| spellingShingle | Yasir Ezalden Noori Alkashab Inam S. Arif Manal M. Younus Mohammed M. Mohammed Abdullah M. Alrawi Salim Hamadi Analysis of Favipiravir Adverse Drug Reactions during COVID-19 Pandemic: A Retrospective Study Based on Iraqi Pharmacovigilance Center Database Al-Mustansiriyah Journal of Pharmaceutical Sciences COVID-19 SARS-COV-2 Favipiravir coronavirus pharmacovigilance Iraq |
| title | Analysis of Favipiravir Adverse Drug Reactions during COVID-19 Pandemic: A Retrospective Study Based on Iraqi Pharmacovigilance Center Database |
| title_full | Analysis of Favipiravir Adverse Drug Reactions during COVID-19 Pandemic: A Retrospective Study Based on Iraqi Pharmacovigilance Center Database |
| title_fullStr | Analysis of Favipiravir Adverse Drug Reactions during COVID-19 Pandemic: A Retrospective Study Based on Iraqi Pharmacovigilance Center Database |
| title_full_unstemmed | Analysis of Favipiravir Adverse Drug Reactions during COVID-19 Pandemic: A Retrospective Study Based on Iraqi Pharmacovigilance Center Database |
| title_short | Analysis of Favipiravir Adverse Drug Reactions during COVID-19 Pandemic: A Retrospective Study Based on Iraqi Pharmacovigilance Center Database |
| title_sort | analysis of favipiravir adverse drug reactions during covid 19 pandemic a retrospective study based on iraqi pharmacovigilance center database |
| topic | COVID-19 SARS-COV-2 Favipiravir coronavirus pharmacovigilance Iraq |
| url | https://ajps.uomustansiriyah.edu.iq/index.php/AJPS/article/view/1069 |
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