First vs. multiple cannabis-induced psychotic episodes: Is inpatient treatment any different?

Introduction Recent studies reported very high cumulative risk for a patient who had cannabis-induced psychosis to be diagnosed with a schizophrenia spectrum disorder. Objectives We aim to compare sociodemographic and clinical characteristics, treatment and discharge plan in cannabis-induced fir...

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Main Authors: F. Andrade, V. Covelo, A.S. Machado
Format: Article
Language:English
Published: Cambridge University Press 2021-04-01
Series:European Psychiatry
Subjects:
Online Access:https://www.cambridge.org/core/product/identifier/S092493382101436X/type/journal_article
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author F. Andrade
V. Covelo
A.S. Machado
author_facet F. Andrade
V. Covelo
A.S. Machado
author_sort F. Andrade
collection DOAJ
description Introduction Recent studies reported very high cumulative risk for a patient who had cannabis-induced psychosis to be diagnosed with a schizophrenia spectrum disorder. Objectives We aim to compare sociodemographic and clinical characteristics, treatment and discharge plan in cannabis-induced first psychosis episode (CI-FEP) vs. multiple cannabis-induced psychotic episodes (CI-MEP) inpatients. Methods Retrospective observational study of inpatient episodes with a discharge diagnosis of cannabis-induced psychosis between January 1st, 2018 and December 31st, 2019 in the Psychiatry Service of CHUSJ. Descriptive analysis of the results was performed using the SPSS software, version 26.0. Results Our sample included 61 inpatients, 19 (31.1%) with CI-FEP and 42 (68.9%) with CI-MEP. CI-MEP group had a median of 1±0,234 previous hospital admissions. CI-MEP group has 10,0 higher odds of being discharged in outpatient compulsory treatment (CI 95% 1,21-82,50, p=0,013) and 6.0 odds of being treated with long-acting injectable antipsychotics (LAIAP) (CI 95% 1,79-20,31, p=0,002) when compared to CI-FEP group. Having multiple cannabis-induced psychotic episodes was associated with future admissions to psychiatry unit (OR 4,85 (95% CI 1,23-19,15, p=0,018). We found no statistically significant differences regarding the sociodemographic and clinical characteristics, use habits and discharge plan between the two groups. Conclusions Patients with multiple psychotic episodes due to cannabis use are more likely to have a LAIAP prescription, be discharged in compulsory outpatient regimen and be readmitted in to psychiatric inpatient unit. Considering the prevalence of CI-MEP and the risk of chronicity, we need integrative treatment programs to address the specificities of these patients.
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spelling doaj.art-6830600a4371462a8d108ddfa2bf053b2023-11-17T05:06:51ZengCambridge University PressEuropean Psychiatry0924-93381778-35852021-04-0164S538S53810.1192/j.eurpsy.2021.1436First vs. multiple cannabis-induced psychotic episodes: Is inpatient treatment any different?F. Andrade0V. Covelo1A.S. Machado2Psychiatric Service, Centro Hospitalar Universitário de São João, Porto, PortugalPsychiatric Service, Centro Hospitalar Universitário de São João, Porto, PortugalPsychiatric Service, Centro Hospitalar Universitário de São João, Porto, Portugal Introduction Recent studies reported very high cumulative risk for a patient who had cannabis-induced psychosis to be diagnosed with a schizophrenia spectrum disorder. Objectives We aim to compare sociodemographic and clinical characteristics, treatment and discharge plan in cannabis-induced first psychosis episode (CI-FEP) vs. multiple cannabis-induced psychotic episodes (CI-MEP) inpatients. Methods Retrospective observational study of inpatient episodes with a discharge diagnosis of cannabis-induced psychosis between January 1st, 2018 and December 31st, 2019 in the Psychiatry Service of CHUSJ. Descriptive analysis of the results was performed using the SPSS software, version 26.0. Results Our sample included 61 inpatients, 19 (31.1%) with CI-FEP and 42 (68.9%) with CI-MEP. CI-MEP group had a median of 1±0,234 previous hospital admissions. CI-MEP group has 10,0 higher odds of being discharged in outpatient compulsory treatment (CI 95% 1,21-82,50, p=0,013) and 6.0 odds of being treated with long-acting injectable antipsychotics (LAIAP) (CI 95% 1,79-20,31, p=0,002) when compared to CI-FEP group. Having multiple cannabis-induced psychotic episodes was associated with future admissions to psychiatry unit (OR 4,85 (95% CI 1,23-19,15, p=0,018). We found no statistically significant differences regarding the sociodemographic and clinical characteristics, use habits and discharge plan between the two groups. Conclusions Patients with multiple psychotic episodes due to cannabis use are more likely to have a LAIAP prescription, be discharged in compulsory outpatient regimen and be readmitted in to psychiatric inpatient unit. Considering the prevalence of CI-MEP and the risk of chronicity, we need integrative treatment programs to address the specificities of these patients. https://www.cambridge.org/core/product/identifier/S092493382101436X/type/journal_articleCannabisCannabis psychosisschizophréniaFEP
spellingShingle F. Andrade
V. Covelo
A.S. Machado
First vs. multiple cannabis-induced psychotic episodes: Is inpatient treatment any different?
European Psychiatry
Cannabis
Cannabis psychosis
schizophrénia
FEP
title First vs. multiple cannabis-induced psychotic episodes: Is inpatient treatment any different?
title_full First vs. multiple cannabis-induced psychotic episodes: Is inpatient treatment any different?
title_fullStr First vs. multiple cannabis-induced psychotic episodes: Is inpatient treatment any different?
title_full_unstemmed First vs. multiple cannabis-induced psychotic episodes: Is inpatient treatment any different?
title_short First vs. multiple cannabis-induced psychotic episodes: Is inpatient treatment any different?
title_sort first vs multiple cannabis induced psychotic episodes is inpatient treatment any different
topic Cannabis
Cannabis psychosis
schizophrénia
FEP
url https://www.cambridge.org/core/product/identifier/S092493382101436X/type/journal_article
work_keys_str_mv AT fandrade firstvsmultiplecannabisinducedpsychoticepisodesisinpatienttreatmentanydifferent
AT vcovelo firstvsmultiplecannabisinducedpsychoticepisodesisinpatienttreatmentanydifferent
AT asmachado firstvsmultiplecannabisinducedpsychoticepisodesisinpatienttreatmentanydifferent