Hypothalamic remodeling of thyroid hormone signaling during hibernation in the arctic ground squirrel

Arctic ground squirrels hibernating in darkness activate the pars tuberalis - hypothalamus thyroid hormone signaling pathway, remodel hypothalamic tanycytes, and activate the reproductive axis.

Bibliographic Details
Main Authors: Helen E. Chmura, Cassandra Duncan, Ben Saer, Jeanette T. Moore, Brian M. Barnes, C. Loren Buck, Helen C. Christian, Andrew S. I. Loudon, Cory T. Williams
Format: Article
Language:English
Published: Nature Portfolio 2022-05-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-022-03431-8
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author Helen E. Chmura
Cassandra Duncan
Ben Saer
Jeanette T. Moore
Brian M. Barnes
C. Loren Buck
Helen C. Christian
Andrew S. I. Loudon
Cory T. Williams
author_facet Helen E. Chmura
Cassandra Duncan
Ben Saer
Jeanette T. Moore
Brian M. Barnes
C. Loren Buck
Helen C. Christian
Andrew S. I. Loudon
Cory T. Williams
author_sort Helen E. Chmura
collection DOAJ
description Arctic ground squirrels hibernating in darkness activate the pars tuberalis - hypothalamus thyroid hormone signaling pathway, remodel hypothalamic tanycytes, and activate the reproductive axis.
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spelling doaj.art-6832b2903caa4c0e9e095e8e29ccf0e82022-12-22T03:21:26ZengNature PortfolioCommunications Biology2399-36422022-05-015111310.1038/s42003-022-03431-8Hypothalamic remodeling of thyroid hormone signaling during hibernation in the arctic ground squirrelHelen E. Chmura0Cassandra Duncan1Ben Saer2Jeanette T. Moore3Brian M. Barnes4C. Loren Buck5Helen C. Christian6Andrew S. I. Loudon7Cory T. Williams8Institute of Arctic Biology, University of Alaska FairbanksDepartment of Biology and Wildlife, University of Alaska FairbanksCentre for Biological Timing, Faculty of Biology, Medicine and Health, University of ManchesterInstitute of Arctic Biology, University of Alaska FairbanksInstitute of Arctic Biology, University of Alaska FairbanksNorthern Arizona University, Department of Biological SciencesDepartment of Physiology, Anatomy, and Genetics, Le Gros Clark Building, University of OxfordCentre for Biological Timing, Faculty of Biology, Medicine and Health, University of ManchesterInstitute of Arctic Biology, University of Alaska FairbanksArctic ground squirrels hibernating in darkness activate the pars tuberalis - hypothalamus thyroid hormone signaling pathway, remodel hypothalamic tanycytes, and activate the reproductive axis.https://doi.org/10.1038/s42003-022-03431-8
spellingShingle Helen E. Chmura
Cassandra Duncan
Ben Saer
Jeanette T. Moore
Brian M. Barnes
C. Loren Buck
Helen C. Christian
Andrew S. I. Loudon
Cory T. Williams
Hypothalamic remodeling of thyroid hormone signaling during hibernation in the arctic ground squirrel
Communications Biology
title Hypothalamic remodeling of thyroid hormone signaling during hibernation in the arctic ground squirrel
title_full Hypothalamic remodeling of thyroid hormone signaling during hibernation in the arctic ground squirrel
title_fullStr Hypothalamic remodeling of thyroid hormone signaling during hibernation in the arctic ground squirrel
title_full_unstemmed Hypothalamic remodeling of thyroid hormone signaling during hibernation in the arctic ground squirrel
title_short Hypothalamic remodeling of thyroid hormone signaling during hibernation in the arctic ground squirrel
title_sort hypothalamic remodeling of thyroid hormone signaling during hibernation in the arctic ground squirrel
url https://doi.org/10.1038/s42003-022-03431-8
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