Gallbladder Carcinoma Masquerading as Calculous Cholecystitis: A Rare Case Report

The incidence of Gallbladder carcinomas are very rare and may go undetected in radiology. Gallbladder carcinomas account for 1.2% of cancers globally. Gallbladder is the commonest site of cancers of biliary tract and most are adenocarcinomas arising from secretory cells. Most patients are females in...

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Main Authors: Ranjani Mohan, Priavadhana Rajan Prasaad, Meenakshisundaram Kumaresan
Format: Article
Language:English
Published: JCDR Research and Publications Pvt. Ltd. 2023-01-01
Series:National Journal of Laboratory Medicine
Subjects:
Online Access:https://njlm.net/article_FULLTEXT.aspx?issn=0973-709x&year=2023&month=January&volume=12&issue=1&page=PC04%20-%20PC06&id=2691
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author Ranjani Mohan
Priavadhana Rajan Prasaad
Meenakshisundaram Kumaresan
author_facet Ranjani Mohan
Priavadhana Rajan Prasaad
Meenakshisundaram Kumaresan
author_sort Ranjani Mohan
collection DOAJ
description The incidence of Gallbladder carcinomas are very rare and may go undetected in radiology. Gallbladder carcinomas account for 1.2% of cancers globally. Gallbladder is the commonest site of cancers of biliary tract and most are adenocarcinomas arising from secretory cells. Most patients are females in their fourth and fifth decades, presenting with vague symptoms like pain and discomfort in locally advanced disease. Most are diagnosed in cholecystectomies done for calculi, polyp or cholecystitis. Biliary type of adenocarcinoma is the most common histologic subtype reported in the literature. The signet ring cell carcinoma of gallbladder is an uncommon subtype with very few reported cases in the past. Here authors report a case of signet ring cell carcinoma of gallbladder in a 42-year-old female patient who presented with dull aching pain in right hypochondrium for six months. Ultrasound and Computed Tomography (CT) revealed calculous cholecystitis with pericholecystic fluid collection. But the final histopathology revealed an unusual variant of gallbladder carcinoma.
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spelling doaj.art-6832e1c721b14350bc40fa26dffcde382023-01-20T10:04:07ZengJCDR Research and Publications Pvt. Ltd.National Journal of Laboratory Medicine2277-85512455-68822023-01-01121PC04PC0610.7860/NJLM/2023/59023.2691Gallbladder Carcinoma Masquerading as Calculous Cholecystitis: A Rare Case ReportRanjani Mohan0Priavadhana Rajan Prasaad1Meenakshisundaram Kumaresan2Assistant Professor, Department of Pathology, ESIC Medical College and PGIMSR, Chennai, Tamil Nadu, India.Assistant Professor, Department of Pathology, ESIC Medical College and PGIMSR, Chennai, Tamil Nadu, India.Professor and Head, Department of Pathology, ESIC Medical College and PGIMSR, Chennai, Tamil Nadu, India. The incidence of Gallbladder carcinomas are very rare and may go undetected in radiology. Gallbladder carcinomas account for 1.2% of cancers globally. Gallbladder is the commonest site of cancers of biliary tract and most are adenocarcinomas arising from secretory cells. Most patients are females in their fourth and fifth decades, presenting with vague symptoms like pain and discomfort in locally advanced disease. Most are diagnosed in cholecystectomies done for calculi, polyp or cholecystitis. Biliary type of adenocarcinoma is the most common histologic subtype reported in the literature. The signet ring cell carcinoma of gallbladder is an uncommon subtype with very few reported cases in the past. Here authors report a case of signet ring cell carcinoma of gallbladder in a 42-year-old female patient who presented with dull aching pain in right hypochondrium for six months. Ultrasound and Computed Tomography (CT) revealed calculous cholecystitis with pericholecystic fluid collection. But the final histopathology revealed an unusual variant of gallbladder carcinoma.https://njlm.net/article_FULLTEXT.aspx?issn=0973-709x&year=2023&month=January&volume=12&issue=1&page=PC04%20-%20PC06&id=2691gallbladder cancerimmunohistochemistrysignet ring cell carcinoma
spellingShingle Ranjani Mohan
Priavadhana Rajan Prasaad
Meenakshisundaram Kumaresan
Gallbladder Carcinoma Masquerading as Calculous Cholecystitis: A Rare Case Report
National Journal of Laboratory Medicine
gallbladder cancer
immunohistochemistry
signet ring cell carcinoma
title Gallbladder Carcinoma Masquerading as Calculous Cholecystitis: A Rare Case Report
title_full Gallbladder Carcinoma Masquerading as Calculous Cholecystitis: A Rare Case Report
title_fullStr Gallbladder Carcinoma Masquerading as Calculous Cholecystitis: A Rare Case Report
title_full_unstemmed Gallbladder Carcinoma Masquerading as Calculous Cholecystitis: A Rare Case Report
title_short Gallbladder Carcinoma Masquerading as Calculous Cholecystitis: A Rare Case Report
title_sort gallbladder carcinoma masquerading as calculous cholecystitis a rare case report
topic gallbladder cancer
immunohistochemistry
signet ring cell carcinoma
url https://njlm.net/article_FULLTEXT.aspx?issn=0973-709x&year=2023&month=January&volume=12&issue=1&page=PC04%20-%20PC06&id=2691
work_keys_str_mv AT ranjanimohan gallbladdercarcinomamasqueradingascalculouscholecystitisararecasereport
AT priavadhanarajanprasaad gallbladdercarcinomamasqueradingascalculouscholecystitisararecasereport
AT meenakshisundaramkumaresan gallbladdercarcinomamasqueradingascalculouscholecystitisararecasereport