Mitochondrial encephalopathy, lactic acidosis, and stroke-like episodes syndrome (MELAS): diagnostic criteria, features of epileptic seizures, and treatment approaches by the example of a clinical case

The paper describes a patient with mitochondrial encephalopathy, lactic acidosis, and stroke-like episodes syndrome (MELAS). The features of  the course and therapy of epilepsy in MELAS are discussed. The disease  is known for its late diagnosis when years elapse from the onset of the  clinical mani...

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Main Authors: M. A. Yamin, I. V. Chernikova, L. V. Araslanova, P. A. Shevkun
Format: Article
Language:Russian
Published: IMA-PRESS LLC 2017-12-01
Series:Неврология, нейропсихиатрия, психосоматика
Subjects:
Online Access:https://nnp.ima-press.net/nnp/article/view/799
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author M. A. Yamin
I. V. Chernikova
L. V. Araslanova
P. A. Shevkun
author_facet M. A. Yamin
I. V. Chernikova
L. V. Araslanova
P. A. Shevkun
author_sort M. A. Yamin
collection DOAJ
description The paper describes a patient with mitochondrial encephalopathy, lactic acidosis, and stroke-like episodes syndrome (MELAS). The features of  the course and therapy of epilepsy in MELAS are discussed. The disease  is known for its late diagnosis when years elapse from the onset of the  clinical manifestations to diagnosis. The paper presents clinical criteria  for the diagnosis of MELAS and the specific features of brain neuroimaging changes that allow identification of the disease at an early stage.
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spelling doaj.art-6833e9b2606544d3b2ba977e467cdd192023-03-13T08:42:17ZrusIMA-PRESS LLCНеврология, нейропсихиатрия, психосоматика2074-27112310-13422017-12-0194656910.14412/2074-2711-2017-4-65-69694Mitochondrial encephalopathy, lactic acidosis, and stroke-like episodes syndrome (MELAS): diagnostic criteria, features of epileptic seizures, and treatment approaches by the example of a clinical caseM. A. Yamin0I. V. Chernikova1L. V. Araslanova2P. A. Shevkun3Regional Consulting and Diagnostic CenterRostov State Medical University, Ministry of Health of RussiaRegional Consulting and Diagnostic CenterRegional Consulting and Diagnostic CenterThe paper describes a patient with mitochondrial encephalopathy, lactic acidosis, and stroke-like episodes syndrome (MELAS). The features of  the course and therapy of epilepsy in MELAS are discussed. The disease  is known for its late diagnosis when years elapse from the onset of the  clinical manifestations to diagnosis. The paper presents clinical criteria  for the diagnosis of MELAS and the specific features of brain neuroimaging changes that allow identification of the disease at an early stage.https://nnp.ima-press.net/nnp/article/view/799melasdiagnostic criterianeuroimaging signscase report
spellingShingle M. A. Yamin
I. V. Chernikova
L. V. Araslanova
P. A. Shevkun
Mitochondrial encephalopathy, lactic acidosis, and stroke-like episodes syndrome (MELAS): diagnostic criteria, features of epileptic seizures, and treatment approaches by the example of a clinical case
Неврология, нейропсихиатрия, психосоматика
melas
diagnostic criteria
neuroimaging signs
case report
title Mitochondrial encephalopathy, lactic acidosis, and stroke-like episodes syndrome (MELAS): diagnostic criteria, features of epileptic seizures, and treatment approaches by the example of a clinical case
title_full Mitochondrial encephalopathy, lactic acidosis, and stroke-like episodes syndrome (MELAS): diagnostic criteria, features of epileptic seizures, and treatment approaches by the example of a clinical case
title_fullStr Mitochondrial encephalopathy, lactic acidosis, and stroke-like episodes syndrome (MELAS): diagnostic criteria, features of epileptic seizures, and treatment approaches by the example of a clinical case
title_full_unstemmed Mitochondrial encephalopathy, lactic acidosis, and stroke-like episodes syndrome (MELAS): diagnostic criteria, features of epileptic seizures, and treatment approaches by the example of a clinical case
title_short Mitochondrial encephalopathy, lactic acidosis, and stroke-like episodes syndrome (MELAS): diagnostic criteria, features of epileptic seizures, and treatment approaches by the example of a clinical case
title_sort mitochondrial encephalopathy lactic acidosis and stroke like episodes syndrome melas diagnostic criteria features of epileptic seizures and treatment approaches by the example of a clinical case
topic melas
diagnostic criteria
neuroimaging signs
case report
url https://nnp.ima-press.net/nnp/article/view/799
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AT ivchernikova mitochondrialencephalopathylacticacidosisandstrokelikeepisodessyndromemelasdiagnosticcriteriafeaturesofepilepticseizuresandtreatmentapproachesbytheexampleofaclinicalcase
AT lvaraslanova mitochondrialencephalopathylacticacidosisandstrokelikeepisodessyndromemelasdiagnosticcriteriafeaturesofepilepticseizuresandtreatmentapproachesbytheexampleofaclinicalcase
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