Outcomes of Endoscopic Intervention Using Over-the-Scope Clips for Anastomotic Leakage Involving Secondary Fistula after Gastrointestinal Surgery: A Japanese Multicenter Case Series
Background: The over-the-scope clip (OTSC) is a highly effective clipping device for refractory gastrointestinal disease. However, Japanese data from multicenter studies for anastomotic leakage (AL) involving a secondary fistula after gastrointestinal surgery are lacking. Therefore, this study evalu...
| Main Authors: | , , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-09-01
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| Series: | Diagnostics |
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| Online Access: | https://www.mdpi.com/2075-4418/13/18/2997 |
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| author | Naoya Tada Hideki Kobara Tomoaki Tashima Hayato Fukui Satoshi Asai Takumi Ichinona Koji Kojima Kunihisa Uchita Noriko Nishiyama Joji Tani Asahiro Morishita Akihiro Kondo Keiichi Okano Hajime Isomoto Kazuki Sumiyama Tsutomu Masaki Osamu Dohi |
| author_facet | Naoya Tada Hideki Kobara Tomoaki Tashima Hayato Fukui Satoshi Asai Takumi Ichinona Koji Kojima Kunihisa Uchita Noriko Nishiyama Joji Tani Asahiro Morishita Akihiro Kondo Keiichi Okano Hajime Isomoto Kazuki Sumiyama Tsutomu Masaki Osamu Dohi |
| author_sort | Naoya Tada |
| collection | DOAJ |
| description | Background: The over-the-scope clip (OTSC) is a highly effective clipping device for refractory gastrointestinal disease. However, Japanese data from multicenter studies for anastomotic leakage (AL) involving a secondary fistula after gastrointestinal surgery are lacking. Therefore, this study evaluated the efficacy and safety of OTSC placement in Japanese patients with such conditions. Methods: We retrospectively collected data from 28 consecutive patients from five institutions who underwent OTSC-mediated closure for AL between July 2017 and July 2020. Results: The AL and fistula were located in the esophagus (3.6%, <i>n</i> = 1), stomach (10.7%, <i>n</i> = 3), small intestine (7.1%, <i>n</i> = 2), colon (25.0%, <i>n</i> = 7), and rectum (53.6%, <i>n</i> = 15). The technical success, clinical success, and complication rates were 92.9% (26/28), 71.4% (20/28), and 0% (0/28), respectively. An age of <65 years (85.7%), small intestinal AL (100%) and colonic AL (100%), defect size of <10 mm (82.4%), time to OTSC placement > 7 days (84.2%), and the use of simple suction (78.9%) and anchor forceps (80.0%) were associated with higher clinical success rates. Conclusion: OTSC placement is a useful therapeutic option for AL after gastrointestinal surgery. |
| first_indexed | 2024-03-10T22:52:08Z |
| format | Article |
| id | doaj.art-6835c83dda564376b272db0051393edc |
| institution | Directory Open Access Journal |
| issn | 2075-4418 |
| language | English |
| last_indexed | 2024-03-10T22:52:08Z |
| publishDate | 2023-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Diagnostics |
| spelling | doaj.art-6835c83dda564376b272db0051393edc2023-11-19T10:14:28ZengMDPI AGDiagnostics2075-44182023-09-011318299710.3390/diagnostics13182997Outcomes of Endoscopic Intervention Using Over-the-Scope Clips for Anastomotic Leakage Involving Secondary Fistula after Gastrointestinal Surgery: A Japanese Multicenter Case SeriesNaoya Tada0Hideki Kobara1Tomoaki Tashima2Hayato Fukui3Satoshi Asai4Takumi Ichinona5Koji Kojima6Kunihisa Uchita7Noriko Nishiyama8Joji Tani9Asahiro Morishita10Akihiro Kondo11Keiichi Okano12Hajime Isomoto13Kazuki Sumiyama14Tsutomu Masaki15Osamu Dohi16Department of Gastroenterology and Neurology, Faculty of Medicine, Kagawa University, Takamatsu 761-0793, JapanDepartment of Gastroenterology and Neurology, Faculty of Medicine, Kagawa University, Takamatsu 761-0793, JapanDepartment of Gastroenterology, Saitama Medical University International Medical Center, Saitama 350-1298, JapanMolecular Gastroenterology and Hepatology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto 602-8566, JapanDepartment of Gastroenterology, Tane General Hospital, Osaka 550-0025, JapanDepartment of Gastroenterology, Tane General Hospital, Osaka 550-0025, JapanDepartment of Gastroenterology, Kochi Red Cross Hospital, Kochi 780-0026, JapanDepartment of Gastroenterology, Kochi Red Cross Hospital, Kochi 780-0026, JapanDepartment of Gastroenterology and Neurology, Faculty of Medicine, Kagawa University, Takamatsu 761-0793, JapanDepartment of Gastroenterology and Neurology, Faculty of Medicine, Kagawa University, Takamatsu 761-0793, JapanDepartment of Gastroenterology and Neurology, Faculty of Medicine, Kagawa University, Takamatsu 761-0793, JapanDepartment of Gastroenterological Surgery, Faculty of Medicine, Kagawa University, Takamatsu 761-0793, JapanDepartment of Gastroenterological Surgery, Faculty of Medicine, Kagawa University, Takamatsu 761-0793, JapanDivision of Gastroenterology and Nephrology, Faculty of Medicine, Tottori University, Tottori 683-8504, JapanDepartment of Endoscopy, The Jikei University School of Medicine, Tokyo 105-8461, JapanDepartment of Gastroenterology and Neurology, Faculty of Medicine, Kagawa University, Takamatsu 761-0793, JapanMolecular Gastroenterology and Hepatology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto 602-8566, JapanBackground: The over-the-scope clip (OTSC) is a highly effective clipping device for refractory gastrointestinal disease. However, Japanese data from multicenter studies for anastomotic leakage (AL) involving a secondary fistula after gastrointestinal surgery are lacking. Therefore, this study evaluated the efficacy and safety of OTSC placement in Japanese patients with such conditions. Methods: We retrospectively collected data from 28 consecutive patients from five institutions who underwent OTSC-mediated closure for AL between July 2017 and July 2020. Results: The AL and fistula were located in the esophagus (3.6%, <i>n</i> = 1), stomach (10.7%, <i>n</i> = 3), small intestine (7.1%, <i>n</i> = 2), colon (25.0%, <i>n</i> = 7), and rectum (53.6%, <i>n</i> = 15). The technical success, clinical success, and complication rates were 92.9% (26/28), 71.4% (20/28), and 0% (0/28), respectively. An age of <65 years (85.7%), small intestinal AL (100%) and colonic AL (100%), defect size of <10 mm (82.4%), time to OTSC placement > 7 days (84.2%), and the use of simple suction (78.9%) and anchor forceps (80.0%) were associated with higher clinical success rates. Conclusion: OTSC placement is a useful therapeutic option for AL after gastrointestinal surgery.https://www.mdpi.com/2075-4418/13/18/2997over-the-scope clipanastomotic leakagefistulaendoscopic closure |
| spellingShingle | Naoya Tada Hideki Kobara Tomoaki Tashima Hayato Fukui Satoshi Asai Takumi Ichinona Koji Kojima Kunihisa Uchita Noriko Nishiyama Joji Tani Asahiro Morishita Akihiro Kondo Keiichi Okano Hajime Isomoto Kazuki Sumiyama Tsutomu Masaki Osamu Dohi Outcomes of Endoscopic Intervention Using Over-the-Scope Clips for Anastomotic Leakage Involving Secondary Fistula after Gastrointestinal Surgery: A Japanese Multicenter Case Series Diagnostics over-the-scope clip anastomotic leakage fistula endoscopic closure |
| title | Outcomes of Endoscopic Intervention Using Over-the-Scope Clips for Anastomotic Leakage Involving Secondary Fistula after Gastrointestinal Surgery: A Japanese Multicenter Case Series |
| title_full | Outcomes of Endoscopic Intervention Using Over-the-Scope Clips for Anastomotic Leakage Involving Secondary Fistula after Gastrointestinal Surgery: A Japanese Multicenter Case Series |
| title_fullStr | Outcomes of Endoscopic Intervention Using Over-the-Scope Clips for Anastomotic Leakage Involving Secondary Fistula after Gastrointestinal Surgery: A Japanese Multicenter Case Series |
| title_full_unstemmed | Outcomes of Endoscopic Intervention Using Over-the-Scope Clips for Anastomotic Leakage Involving Secondary Fistula after Gastrointestinal Surgery: A Japanese Multicenter Case Series |
| title_short | Outcomes of Endoscopic Intervention Using Over-the-Scope Clips for Anastomotic Leakage Involving Secondary Fistula after Gastrointestinal Surgery: A Japanese Multicenter Case Series |
| title_sort | outcomes of endoscopic intervention using over the scope clips for anastomotic leakage involving secondary fistula after gastrointestinal surgery a japanese multicenter case series |
| topic | over-the-scope clip anastomotic leakage fistula endoscopic closure |
| url | https://www.mdpi.com/2075-4418/13/18/2997 |
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