Nanopore MinION Sequencing Reveals Possible Transfer of blaKPC–2 Plasmid Across Bacterial Species in Two Healthcare Facilities

Nanopore MinION Sequencing Reveals Possible Transfer of blaKPC–2 Plasmid Across Bacterial Species in Two Healthcare Facilities

Carbapenemase-producing Enterobacteriaceae are a major threat to global public health. Klebsiella pneumoniae carbapenemase (KPC) is the most commonly identified carbapenemase in the United States and is frequently found on mobile genetic elements including plasmids, which can be horizontally transmi...

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Bibliographic Details
Main Authors: Catharine Prussing, Emily A. Snavely, Navjot Singh, Pascal Lapierre, Erica Lasek-Nesselquist, Kara Mitchell, Wolfgang Haas, Rita Owsiak, Elizabeth Nazarian, Kimberlee A. Musser
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Microbiology
Subjects:
carbapenem-resistant enterobacteriaceae
klebsiella pneumoniae carbapenemase
horizontal gene transfer
plasmids
long-read sequencing
hybrid genome assembly
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2020.02007/full

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